Metabolic Disorders and Cancer: Store-Operated Ca2+ Entry in Cancer - Focus on IP3R-Mediated Ca2+ Release from Intracellular Stores and Its Role in Migration and Invasion KU Leuven
Store-operated calcium entry (SOCE) plays important roles in a multitude of cellular processes, from muscle contraction to cellular proliferation and migration. Dysregulation of SOCE is responsible for the advancement of multiple diseases, ranging from immune diseases, myopathies, to terminal ones like cancer. Naturally, SOCE has been a focus of many studies and review papers which, however, primarily concentrated on the principal players ...