Projecten
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Planning, admission and marketing Universiteit Gent
20083 Planning, admission and marketing Universiteit Gent
Targeting Mfrn2 to Inhibit Metastatic Cancers. (MetaIron) Vlaams Instituut voor Biotechnologie
Tackling cancer and in particular metastasis formation as a metabolic disease, mechanistically dissect the metabolic vulnerabilities of (metastasizing) cancer cells in the context of the tumor microenvironment and the metastatic niche to define novel therapeutic approaches to prevent cancer progression.
Training van de volgende generatie Europese glioblastoma (translationele) onderzoekers, om nauwkeurige targeting van de micro-omgeving van de hersentumor op te lossen KU Leuven
Isocitrate dehydrogenase wildtype (IDHwt) glioblastoma (GBM) is the most frequent, aggressive and lethal brain tumour. It has a universally fatal prognosis with 85% of patients dying within two years. Effective precision medicine therapies are thus urgently required. This can only be achieved by focused multi-sectoral collaborations in innovative research disciplines. Overall, GLIORESOLVE will exploit the intractability of GBM to address ...
Targeting bicarbonate transport as a “first-in-class” therapeutic strategy to promote CD8+ T cell fitness and enhance cancer immunotherapy Vlaams Instituut voor Biotechnologie
Bridging the current gap between cancer cell biology - autonomous traits of malignant cells - and tumor biology - non-autonomous traits where, the unique features of the TME along with its cellular cross-talks are the main drivers of malignancy, understanding of the environmental cues and molecular pathways that participate in the interaction between cancer cells and stromal cells within the harsh TME.
Training the next-generation of European GLIOblastoma (translational) researchers, to RESOLVE precision targeting of the brain tumour microenvironment. Vlaams Instituut voor Biotechnologie
Conducting a comprehensive investigation that defines the dialogues of heterogeneous tumor cell subtypes, and the vasculature and immune cells in the distinct tumor vascular niches in response during progression as well as targeted therapies including antiangiogenic and immune-modulating therapies.
Protease-geleide tumor targeting voor een doorbraak in de diagnose en behandeling van kanker (OncoProTools). Universiteit Antwerpen
Moleculaire Beeldvorming en Radiologie (MIRA), Medische biochemie, Technische Universität Dresden, University of Copenhagen, University of Bern, Agencia Estatal Consejo Superior de Investigaciones Científicas (CSIC), Johannes Gutenberg - Universität Mainz, Helmholtz-Zentrum Dresden-Rossendorf, Semmelweis University, Universidad Autónoma de Madrid, Universidade de Lisboa, Università di Bologna, Medicinale chemie (UAMC)
Europa heeft een hoge incidentie aan kankers: in 2020 werd bij 2,7 miljoen EU-burgers de ziekte vastgesteld en verloren 1,3 miljoen burgers hun leven eraan. eraan. Deze tol zal naar verwachting verder stijgen, vooral omdat de Europese bevolking vergrijst: in 2035 zal kanker de belangrijkste doodsoorzaak in de EU zijn. In 2021 publiceerde de EC haar "Europe's Beating Cancer Plan" (EBCP), waarin wordt opgeroepen tot een grote impuls voor ...
Versterking van geavanceerde doctoraatsopleidingen in innovatieve geneesmiddelen (colon targeting drugs) KU Leuven
The Colon Targeting Network (COLOTAN) is a European Training Network that will train 13 Early Stage Researchers (ESRs) in (bio)pharmaceutical sciences to improve targeting of oral drugs to the colon.
Oral administration of drugs is the preferred delivery route due to its non-invasiveness and convenience for the patient. However, issues related to solubility, absorption, and metabolism often cause oral drug candidate attrition. Oral ...
Targeting Tau-induced cognitive decline with antisense oligonucleotides to synaptogyrin-3 Vlaams Instituut voor Biotechnologie
Studying how the brain operates and how brain function is affected by neurodegenerative diseases, specifically Parkinson’s disease and Tauopathies, analysing neuronal communication abd synaptic survival.