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Plasmodium malariae after successful treatment of P. falciparum malaria with artemether-lumefantrine Universiteit Gent Instituut voor Tropische Geneeskunde

Tijs Tournoy, Anna Rosanas-Urgell, Marjan Van Esbroeck, Emmanuel Bottieau, Ralph Huits
We described a case of Plasmodium malariae malaria in a traveler returning from the Democratic Republic of Congo to Belgium. This occurred despite successful artemether-lumefantrine treatment for Plasmodium falciparum three weeks earlier and in the absence of re-exposure in an endemic area. We discuss possible explanations for this unusual observation. (C) 2022 The Authors. Published by Elsevier Ltd on behalf of International Society for ...

Malaria control by antivectorial measures in a zone of chloroquine-resistant malaria: a successful programme in a rice growing area of the Rusizi valley Instituut voor Tropische Geneeskunde

Marc Coosemans, M Barutwanayo
Within a large project for the socio-economic development of the rice growing area of the Rusizi valley in Burundi, a malarial control programme has been set up. This programme has several components: improvement of curative services, promotion of use of impregnated mosquito nets, and use of environmental engineering and indoor spraying with residual insecticides to control infection

Maplaria: a user friendly web-application for spatio-temporal malaria prevalence mapping Instituut voor Tropische Geneeskunde

Emanuele Giorgi, Peter Macharia, Jack Woodmansey, Robert W Snow, Barry Rowlingson

BACKGROUND: Model-based geostatistical (MBG) methods have been extensively used to map malaria risk using community survey data in low-resource settings where disease registries are incomplete or non-existent. However, the wider adoption of MBG methods by national control programmes to inform health policy decisions is hindered by the lack of advanced statistical expertise and suitable computational equipment. Here, Maplaria, an interactive, ...

Geostatistical analysis of Malawi's changing malaria transmission from 2010 to 2017 Instituut voor Tropische Geneeskunde

Michael Give Chipeta, Emanuele Giorgi, Donnie Mategula, Peter Macharia, Chimwemwe Ligomba, Alinane Munyenyembe, James Chirombo, Austin Gumbo, Dianne J Terlouw, Robert W Snow, et al.

Background: The prevalence of malaria infection in time and space provides important information on the likely sub-national epidemiology of malaria burdens and how this has changed following intervention. Model-based geostatitics (MBG) allow national malaria control programmes to leverage multiple data sources to provide predictions of malaria prevalance by district over time. These methods are used to explore the possible changes in malaria ...

Respiratory virus-associated severe acute respiratory illness and viral clustering in Malawian children in a setting with a high prevalence of HIV infection, malaria, and malnutrition Instituut voor Tropische Geneeskunde

Ingrid Peterson, Naor Bar-Zeev, Neil Kennedy, Antonia Ho, Laura Newberry, Miguel A SanJoaquin, Mavis Menyere, Maaike Alaerts, Gugulethu Mapurisa, Moses Chilombe, et al.

BACKGROUND:  We used data from 4 years of pediatric severe acute respiratory illness (SARI) sentinel surveillance in Blantyre, Malawi, to identify factors associated with clinical severity and coviral clustering.

METHODS:  From January 2011 to December 2014, 2363 children aged 3 months to 14 years presenting to the hospital with SARI were enrolled. Nasopharyngeal aspirates were tested for influenza virus and other respiratory viruses. ...

Mangrove horseshoe crab (Carcinoscorpius rotundicauda Latreille, 1802) populations reveal genetic break in Strait of Malacca, with connectivity along southern coasts of Peninsular Malaysia Vrije Universiteit Brussel

Nur Fairuz-Fozi, Ludwig Triest, Nurul Ashikin Mat Zauki, Anne Marie Kaben, Bryan Raveen Nelson, Anil Chatterji, Mohd Fadzil Akhir, Behara Satyanarayana, Farid Dahdouh Guebas

The mangrove horseshoe crab, Carcinoscorpius rotundicauda, has divergent populations between the east and west coasts of Peninsular Malaysia, with the southern coast acting as a land barrier. The actual position of such a genetic break along Peninsular Malaysia as well as the connectivity status of the southernmost C. rotundicauda populations with east and west coast populations remain unexplored, however. The aim was to investigate the ...

Evaluation of a rapid diagnostic test (CareStartTM Malaria HRP-2/pLDH (Pf/pan) Combo Test) for the diagnosis of malaria in a reference setting Instituut voor Tropische Geneeskunde

J Maltha, Philippe Gillet, Emmanuel Bottieau, Lieselotte Cnops, Marjan Van Esbroeck, Jan Jacobs
ABSTRACT: BACKGROUND: Malaria Rapid Diagnostic Tests (RDTs) are widely used for diagnosing malaria. The present retrospective study evaluated the CareStartTM Malaria HRP-2/pLDH (Pf/pan) Combo Test targeting the Plasmodium falciparum specific antigen histidine-rich protein (HRP-2) and the pan-Plasmodium antigen lactate dehydrogenase (pLDH) in a reference setting. METHODS: The CareStartTM Malaria HRP-2/pLDH (Pf/pan) Combo Test was evaluated on a ...

Evaluation of the rapid diagnostic test CareStart pLDH Malaria (Pf-pLDH/pan-pLDH) for the diagnosis of malaria in a reference setting Instituut voor Tropische Geneeskunde

M. Heutmekers, P. Gillet, J. Maltha, A. Scheirlinck, L. Cnops, Emmanuel Bottieau, Marjan Van Esbroeck, Jan Jacobs
BACKGROUND: The present study evaluated CareStart pLDH Malaria, a three-band rapid diagnostic test detecting Plasmodium falciparum-specific parasite lactate dehydrogenase (Pf-pLDH) and pan Plasmodium-specific pLDH (pan-pLDH) in a reference setting. METHODS: CareStart pLDH was retrospectively and prospectively assessed with a panel of stored (n = 498) and fresh (n = 77) blood samples obtained in international travelers suspected of malaria. Both ...