Towards the development of norovirus antiviral drugs: zebrafish larvae as an innovative model system to study the replication of human norovirus KU Leuven
Human noroviruses (HuNoVs) are single stranded, positive sense RNA viruses belonging to the Caliciviridae family. HuNoV infections result in vomiting and watery non-bloody diarrhea. Infections occur worldwide and are an important health issue that affects all age groups, resulting annually in 200,000 deaths. Infections occur via the fecal-oral route, by consumption of contaminated food or water and by person-to-person contact. HuNoV is very ...