Integrative Structural Biology Approach to Intermediate Filaments KU Leuven
Our research focuses on the three-dimensional structure of intermediate filaments (IF). IFs alongside with microtubules and actin microfilaments form filamentous system of the eukaryotic cytoskeleton. There are six different types of IFs that function in different cells. Their main role is to provide reinforcement to the cell to withstand external stress and strain. The number of diseases associated with mutations in IF genes is constantly ...