Publicaties
Immunosenescence and immune exhaustion are associated with levels of protein-bound uremic toxins in patients on hemodialysis Universiteit Gent
Impact of Immunosenescence in Older Kidney Transplant Recipients: Associated Clinical Outcomes and Possible Risk Stratification for Immunosuppression Reduction KU Leuven
Effects of Physical Exercise on Markers of Cellular Immunosenescence Vrije Universiteit Brussel
Aging affects negatively the immune system, defined as immunosenescence, which increases the susceptibility of elderly persons to infection, autoimmune disease, and cancer. There are strong indications that physical exercise in elderly persons may prevent the age-related decline in immune response without significant side effects. Consequently, exercise is being considered as a safe mode of intervention to reduce immunosenescence. The aim of ...
Shifts in subsets of CD8+ T-cells as evidence of immunosenescence in patients with cancers affecting the lungs Vrije Universiteit Brussel
BACKGROUND: Shifts in CD8+ T-cell subsets that are hallmarks of immunosenescence are observed in ageing and in conditions of chronic immune stimulation. Presently, there is limited documentation of such changes in lung cancer and other malignancies affecting the lungs.
METHODS: Changes in CD8+ T-cell subsets, based on the expression of CD28 and CD57, were analysed in patients with various forms of cancer affecting the lungs, ...