Light distribution device, illumination system and imaging system for imaging of samples within microscopy Interuniversitair Micro-Electronica Centrum vzw
The invention discloses a device that allows for a large FOV cSIM imaging capable of super-resolution (fluorescence) microscopy (including next-generation sequencing) with low footprint of the PIC components. Specifically, the illumination patterns in the slab region are formed by interference of slab modes generated from evanescent beam expanders. The key innovative step is the usage and geometrical orientation of the evanescent beam expanders for interference pattern generation. The sample placed on top of the interference region of the slab is illuminated by the evanescent tails of the ...