Publicaties
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Metabolomic profiling of the glucocorticoid status of Holstein-Friesian cows by high-resolution mass spectrometry upon administration of prednisolone Universiteit Gent
Identification and characterization of quaternary ammonium compounds in Flemish indoor dust by ion-mobility high-resolution mass spectrometry Universiteit Antwerpen
Quaternary ammonium compounds (QACs) are a class of surfactants commonly used in disinfecting and cleaning products. Their use has substantially increased during the COVID-19 pandemic leading to increasing human exposure. QACs have been associated with hypersensitivity reactions and an increased risk of asthma. This study introduces the first identification, characterization and semi-quantification of QACs in European indoor dust using ...
Advanced data analytics for high-dimensional mass spectrometry and high-resolution digital pathology Universiteit Hasselt
Geavanceerde data-analysetechnieken hebben een revolutie teweeggebracht in het veld van hoog-dimensionale massaspectrometrie en hoge resolutie digitale pathologie. Deze technieken stellen ons in staat om waardevolle inzichten te verkrijgen uit complexe datasets en dragen bij aan het verbeteren van de diagnose van ziekten, gepersonaliseerde geneeskunde en biomedisch onderzoek. In deze context spelen geavanceerde data-analyse tools een cruciale ...
Comprehensive suspect screening for the identification of contaminants of emerging concern in urine of Flemish adolescents by liquid chromatography high-resolution mass spectrometry Universiteit Antwerpen
The increasing human exposure to contaminants of emerging concern (CECs) cannot be fully assessed by targeted biomonitoring methods alone as these are limited to a subset of known analytes. On the contrary, suspect screening approaches based on liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) allow the simultaneous detection of a high number of CECs and/or their (predicted) metabolites leading to a more comprehensive ...
Identification of novel halogenated naturally occurring compounds in marine biota by high-resolution mass spectrometry and combined screening approaches Universiteit Antwerpen
Marine animals, plants or bacteria are a source of bioactive naturally-occurring halogenated compounds (NHCs) such as bromophenols (BPs), bromoanisoles (BAs) and hydroxylated or methoxylated analogues of polybrominated diphenyl ethers (HO-PBDEs, MeO-PBDEs) and bromobiphenyls (HO-BBs, MeO-BBs). This study applied a comprehensive screening approach using liquid chromatography high-resolution mass spectrometry and combining target, suspect and ...
Application of liquid chromatography coupled to high-resolution mass spectrometry to measure urinary cortisol in loose housed sows Universiteit Gent
Non-target screening with high-resolution mass spectrometry Universiteit Antwerpen
In this article, a dataset from a collaborative non-target screening trial organised by the NORMAN Association is used to review the state-of-the-art and discuss future perspectives of non-target screening using high-resolution mass spectrometry in water analysis. A total of 18 institutes from 12 European countries analysed an extract of the same water sample collected from the River Danube with either one or both of liquid and gas ...