Publicaties

Soil heterogeneity has been shown to enhance plant diversity, but its effect on grassland productivity is less clear. Even less is known about the effect of plant clumping (intraspecific aggregation) and its potential interaction with soil heterogeneity. The combined effects of soil 3D spatial heterogeneity and species clumping were experimentally studied in grassland mesocosms consisting of four grassland species. These species were planted in ...

Myocardial heterogeneity is well appreciated and widely documented, from sub-cellular to organ levels. This paper reviews significant achievements of the group, led by Professor Vladimir S. Markhasin, Russia, who was one of the pioneers in studying and interpreting the relevance of cardiac functional heterogeneity.

International trade affects us all. It expands markets for firms to thrive and increases varieties to satisfy consumers. From waking up with a coffee grown on Brazilian trees to closing a light manufactured in China at night, our daily routines are riddled with products that can be provided by firms located across the world. Not every firm chooses to do so though. Firms are different, heterogeneous, and only those that are sufficiently ...

Spatial heterogeneity of cells in liver biopsies can be used as biomarker for disease severity of patients. This heterogeneity can be quantified by non -parametric statistics of point pattern data, which make use of an aggregation of the point locations. The method and scale of aggregation are usually chosen ad hoc, despite values of the aforementioned statistics being heavily dependent on them. Moreover, in the context of measuring ...

Downie SR, Salome CM, Verbanck S, Thompson BR, Berend N, King GG. Effect of methacholine on peripheral lung mechanics and ventilation heterogeneity in asthma. J Appl Physiol 114: 770-777, 2013. First published January 31, 2013; doi: 10.1152/japplphysiol.01198.2012.-The forced oscillation technique (FOT) and multiple-breath nitrogen washout (MBNW) are noninvasive tests that are potentially sensitive to peripheral airways, with MBNW indexes being ...

Background: Disease burden is not evenly distributed within a population; this uneven distribution can be due to individual heterogeneity in progression rates between disease stages. Composite measures of disease burden that are based on disease progression models, such as the disability-adjusted life year (DALY), are widely used to quantify the current and future burden of infectious diseases. Our goal was to investigate to what extent ignoring ...

As data availability improves, the gravity model of international trade is used to study the flow of trade over increasingly long periods of time. This puts pressure on the standard assumption that constant bilateral fixed effects are sufficient to control for unobserved heterogeneity. When looking across decades rather than years, changes in the economic landscape will affect both explanatory and dependent variables, thus biasing the results. ...

Promoting bicycling and making it attractive requires appropriate infrastructure. Sociode-mographic characteristics, frequency and experiences of bike use, and purpose of bicycle trips can affect preferences towards bicycle infrastructure facilities in urban areas. Hence, this study aims to explore the heterogeneity in the perceived importance of bicycle infrastructure facility attributes in various cyclist groups based on gender, age, weekly ...

The organization and interaction between hepatocytes and other hepatic non-parenchymal cells plays a pivotal role in maintaining normal liver function and structure. Although spatial heterogeneity within the tumor micro environment has been proven to be a fundamental feature in cancer progression, the role of liver tissue topology and micro-environmental factors in the context of liver damage in chronic infection has not been widely studied yet. ...