Hepatocyte growth factor/c-Met signalling is important for the selection of transplanted hepatocytes Vrije Universiteit Brussel
BACKGROUND: At present hepatocyte transplantation is a promising option for cellular therapy of end-stage liver diseases. However, the underlying molecular mechanisms need to be better defined in order to translate this technique into clinical use. This study investigated the cursiv relevance of hepatocyte growth factor (HGF)/c-Met signalling for hepatocyte repopulation after transplantion.
METHODS: Wild-type mice (c-Met(loxP/loxP)) ...