Publicaties
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Hidden Aggregation Hot-Spots on Human Apolipoprotein E: A Structural Study KU Leuven
Human apolipoprotein E (apoE) is a major component of lipoprotein particles, and under physiological conditions, is involved in plasma cholesterol transport. Human apolipoprotein E found in three isoforms (E2; E3; E4) is a member of a family of apolipoproteins that under pathological conditions are detected in extracellular amyloid depositions in several amyloidoses. Interestingly, the lipid-free apoE form has been shown to be co-localized with ...
Avoiding hot-spots in Microwave-assisted Pd/C catalysed reactions by using the biomass derived solvent gamma-Valerolactone KU Leuven
Herein, we report the use of γ-valerolactone as a new biomass-derived reaction medium for microwave assisted organic synthesis. The interaction of this solvent with microwaves and its heating profile under microwave irradiation has been fully characterized for the first time, demonstrating its stability and the applicability in microwave assisted Pd/C catalysed reactions avoiding the arcing phenomena frequently observed in these conditions. The ...
A numerical evaluation of structural hot-spot stress methods in rib-to-deck joint of orthotropic steel deck Universiteit Gent
This study numerically investigates the limitations of structural hot-spot stress (SHSS) methods and proposes a guideline for the calculation of hot-spot stresses, which can be used for the better evaluation of fatigue-related problems. Four different SHSS evaluation methods have been applied to the rib-to-deck (RD) welded joint in orthotropic steel deck (OSD). These methods are used to calculate SHSS at this critical joint utilizing finite ...
A comparison of structural hot-spot stress methods using different finite element techniques Universiteit Gent
In this paper, different methods have been used for the evaluation of structural hot-spot stress (SHSS) near rib-to-deck (RD) welded joint in orthotropic steel deck (OSD). The SHSS at this critical joint is calculated by means of finite element analyses (FEA) based software Siemens NX.12. Different meshing techniques and element sizes have been used for the determination of SHSS. Also, the effect of nodal averaging feature is studied on each ...
Detecting hotspots of urban residents' behaviours based on spatio-temporal clustering techniques Universiteit Gent
Rerouting urban construction transport flows to avoid air pollution hotspots Vrije Universiteit Brussel
Currently, over 96% of the urban population is exposed to exceeding air pollution concentrations. Freight transport daily engenders €61,604 of air pollution health costs in the Brussels-Capital Region (BCR), of which 60% is incurred by vulnerable population segments. The construction sector is responsible for 26.40% of truck traffic in the BCR. This paper examines the exposure effects when off-site construction logistics flows are redirected ...