Publicaties
Gekozen filters:
Gekozen filters:
Antibacterial mouthwash to prevent sexually transmitted infections in men who have sex with men taking HIV pre-exposure prophylaxis (PReGo) Universiteit Antwerpen Instituut voor Tropische Geneeskunde
Background Bacterial sexually transmitted infections (STIs) are highly prevalent among men who have sex with men who use HIV pre-exposure prophylaxis (PrEP), which leads to antimicrobial consumption linked to the emergence of antimicrobial resistance. We aimed to assess use of an antiseptic mouthwash as an antibiotic sparing approach to prevent STIs. Methods We invited people using PrEP who had an STI in the past 24 months to participate in this ...
Prevalence, incidence and seroconversion of HIV and Syphilis infections among pregnant women of South Africa Universiteit Antwerpen
Background: Pregnant women in South Africa suffer from HIV and syphilis infections resulting in negative pregnancy outcomes. Little is known about the prevalence, incidence, seroconversion, and associated risk factors for those attending a midwife run obstetric unit. Methods: A retrospective cohort study was undertaken among pregnant women attending antenatal clinic from January to December 2018. Logistic regression was conducted to determine ...
Characteristics, causes, and outcome of 54 episodes of bloodstream infections in a cohort of HIV patients KU Leuven
Patients infected with human immunodeficiency virus (HIV) have an increased risk for bloodstream infections (BSIs). Published recent data on characteristics, etiology, and outcome of BSIs in HIV patients in high income countries are scarce.
Tribute to John C. Martin at the Twentieth Anniversary of the Breakthrough of Tenofovir in the Treatment of HIV Infections KU Leuven
At Bristol-Myers (BM) (1985-1990), John C. Martin started his HIV career with directing the clinical development of didanosine (ddI) and stavudine (d4T). During this period, he became aware of the acyclic nucleoside phosphonates (ANPs), such as (S)-HPMPA and PMEA, as potential antiviral drugs. Under his impulse, BM got involved in the evaluation of these ANPs, but the merger of BM with Squibb (to become BMS) incited John to leave BM and join ...
Mathematical and statistical models applied to HIV and Hepatitis C co-infection and to nosocomial infections Universiteit Hasselt
In dit proefschrift worden diverse statistische en wiskundige modellen voor HIV en HCV co-infectie en voor nosocomiale infecties gepresenteerd. De modellen werden toegepast op vier verschillende studies, rekening houdend met de doelstellingen en kenmerken van elk onderzoek.
Intravaginal Practices, Vaginal Infections and HIV Acquisition: Systematic Review and Meta-Analysis Universiteit Gent
Background: Intravaginal practices are commonly used by women to manage their vaginal health and sexual life. These practices could, however, affect intravaginal mucosal integrity. The objectives of this study were to examine evidence for associations between: intravaginal practices and acquisition of HIV infection; intravaginal practices and vaginal infections; and vaginal infections and HIV acquisition. Methodology/Principal Findings: We ...
Superimposing incident sexually transmitted infections on HIV phylogram to investigate possible misclassification of men who have sex with men as heterosexuals in a cohort in Antwerp, Belgium Universiteit Antwerpen Instituut voor Tropische Geneeskunde
In this study, we assessed if the superimposition of incident sexually transmitted infections (STIs) on HIV phylogenetic analyses could reveal possible sexual behaviour misclassifications in our HIV-infected population. HIV-1 sequences collected between 1997 and 2014 from 1169 individuals attending a HIV clinic in Antwerp, Belgium were analysed to infer a partial HIV transmission network. Individual demographic, clinical and laboratory data ...
Effect of screening for Neisseria gonorrhoeae and Chlamydia trachomatis on incidence of these infections in men who have sex with men and transgender women taking HIV pre-exposure prophylaxis (the Gonoscreen study) Universiteit Antwerpen
Background Guidelines recommend screening for Neisseria gonorrhoeae and Chlamydia trachomatis at three anatomical sites (urethra, anus, and pharynx) every 3 months (3 × 3) in men who have sex with men (MSM) and transgender women taking HIV pre-exposure prophylaxis (PrEP). We present the first randomised controlled trial to compare the effect of screening versus non-screening for N gonorrhoeae and C trachomatis on the incidence of these ...
Envisioning enabling environments for young women with perinatal infections of HIV in Africa: A participatory creative new-materialist approach. KU Leuven
Background: Targeted due to gender and age in South Africa, young women often must negotiate health and safety in their homes and communities - this is even more challenging for young women living with perinatal infections of Human Immunodeficiency Virus (YWLPHIV). Young people living with perinatal infections face a chronic disease, with treatment including adherence to lifelong ART. We set out to learn more about young women perinatally ...