Publicaties
Genotoxicity of engineered nonamaterials: A critical review (vol 2, 252, 2008) Vrije Universiteit Brussel
Genotoxicity of engineered nanomaterials: a critical review Vrije Universiteit Brussel
Can in vitro mammalian cell genotoxicity test results be used to complement positive results in the Ames test and help predict carcinogenic or in vivo genotoxic activity? Vrije Universiteit Brussel
In vitro toxicity, genotoxicity and antigenotoxicity of Nigella sativa extracts from different geographic locations Universiteit Antwerpen
Pooled analysis of genotoxicity markers in relation to exposure in the Flemish Environment and Health Studies (FLEHS) between 1999 and 2018 KU Leuven Universiteit Hasselt Vrije Universiteit Brussel Universiteit Antwerpen
Genotoxicity of engineered nanoparticles in higher plants KU Leuven
Way forward in case of a false positive in vitro genotoxicity result for a cosmetic substance ? Vrije Universiteit Brussel
In vitro genotoxicity assessment of functional ingredients: DHA, rutin and α-tocopherol Vrije Universiteit Brussel
The in vitro genotoxicity of three compounds widely used as functional ingredients, docosahexaenoic acid (DHA), rutin and α-tocopherol, was assessed. A miniaturized version of the Ames test in Salmonella typhimurium TA97a, TA98, TA100, TA102, and TA1535 strains (following the principles of OECD 471), and the in vitro micronucleus test in TK6 cells (OECD 487) were performed. This strategy is recommended by the European Food Safety Authority ...
Unlocking the Power of Transcriptomic Biomarkers in Qualitative and Quantitative Genotoxicity Assessment of Chemicals Vrije Universiteit Brussel
To modernize genotoxicity assessment and reduce reliance on experimental animals, new approach methodologies (NAMs) that provide human-relevant dose-response data are needed. Two transcriptomic biomarkers, GENOMARK and TGx-DDI, have shown a high classification accuracy for genotoxicity. As these biomarkers were extracted from different training sets, we investigated whether combining the two biomarkers in a human-derived metabolically ...