Publicaties
Gekozen filters:
Gekozen filters:
Araceae embryos as tools for ploidy manipulation and somatic fusion Instituut voor Landbouw-, Visserij- en Voedingsonderzoek
Application of radiation and genetic engineering techniques to improve biocontrol agent performance : a short review Universiteit Gent
Biological control is a potential nonchemical method to manage plant pathogens by beneficial microorganisms. To improve antagonistic potential of biocontrol agents, mutation by radiations, chemicals, and genetic manipulations has been used. Genetic techniques and ionizing radiation containing direct or indirect emissions play the greatest role for selection of useful microorganisms to enhance the efficiency of biological systems. Indeed, genetic ...
Development of Artificial Genetic Systems for Therapeutic Applications KU Leuven
Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are among the most remarkable biomolecules occurring in nature, since they store and transfer all genetic information using only four letters (G, C, A & T or U). In the last 60 years, since the discovery of the structure of nucleic acids, numerous chemically modified nucleosides and nucleotides have been produced and incorporated into oligomeric sequences either by chemical or enzymatic ...
Insights into the genetic control of plant architecture in apple KU Leuven
Apple (Malus x domestica) is one of the most important fruit crops in the world and growers are continuously seeking to improve fruit production and fruit quality while reducing management costs. Yield, homogeneity of fruit quality and the time needed for young trees to reach full production are influenced by the tree's architecture. Tree architecture is currently controlled through orchard management practices, but these practices can be ...
Genetic Diversity, Pollination Ecology and Organoleptic Characteristics of Coffea arabica L. in Ethiopian Moist Forests of Different Management Intensity KU Leuven
800x600 Coffea arabica L.,the world most important commercial coffee species, has its center of originand diversity in the Afromontane rainforests of southwestern Ethiopia. These forests, which harbour themost important C. arabica gene pool, are threatened by increasing ...
Application of enzyme substrate analogues: from inhibitors with anti-mycobacterial properties to synthetic genetic polymers KU Leuven
Part 1: Tuberculosis (TB) is an infectious disease caused by the bacillus Mycobacterium tuberculosis (M. tuberculosis).It is regarded as the leading cause of death from a single infectious agent, even above HIV/AIDS. Although the global tuberculosis incidence has declined marginally over the past two decades, it still affects 10 million people each year and remains out of control in several parts of Africa and Asia. The main threat of TB is the ...
Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury KU Leuven
Genetic disruption of the dystrophin complex produces muscular dystrophy characterized by a fragile muscle plasma membrane leading to excessive muscle degeneration. Two genetic modifiers of Duchenne Muscular Dystrophy implicate the transforming growth factor β (TGFβ) pathway, osteopontin encoded by the SPP1 gene and latent TGFβ binding protein 4 (LTBP4). We now evaluated the functional effect of these modifiers in the context of muscle injury ...
Behavioural evaluation of candidate genetic, environmental and developmental murine models for preclinical schizophrenia research KU Leuven
Valid mouse models of schizophrenia (SCZ) are valuable preclinical research tools to investigate pathogenetic mechanisms and possible treatment strategies for this devastating and poorly understood brain disease. The purpose of current PhD project was to develop and/or evaluate three such models in an extensive test battery that screened for schizophreniform behaviour. The three models focussed on different neurogenetic and environmental factors ...