Publicaties
Quantitative fluorescent antibody technique in human and experimental schistosomiasis Instituut voor Tropische Geneeskunde
Evaluation of the indirect fluorescent antibody test as a diagnostic tool for East Coast fever in eastern Zambia Instituut voor Tropische Geneeskunde
Screening for Trypanosoma brucei gambiense antibodies with the indirect fluorescent antibody test (IFAT); effect of age and previous treatment Instituut voor Tropische Geneeskunde
Follow-up of Leishmania infantum naturally infected dogs treated with allopurinol: immunofluorescence antibody test, ELISA and Western blot Instituut voor Tropische Geneeskunde
Multiplex Staining by Sequential Immunostaining and Antibody Removal on Routine Tissue Sections KU Leuven
Recent progress in molecular diagnosis of sleeping sickness Instituut voor Tropische Geneeskunde
Simultaneous measurement of plasma concentrations of proinsulin and C-peptide and their ratio with a trefoil-type time-resolved fluorescence immunoassay Vrije Universiteit Brussel
BACKGROUND: When the concentrations of 2 or more substances are measured separately, their molar ratios are subject to the additive imprecisions of the different assays. We hypothesized that the cumulative error for concentration ratios of peptides containing a common sequence might be minimized by measuring the peptides simultaneously with a "trefoil-type" immunoassay.
METHODS: As a model of this approach, we developed a dual-label ...
Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity Vrije Universiteit Brussel
The target autoantigens in several organ-specific autoimmune diseases, including type 1 diabetes (T1D), are intracellular membrane proteins, whose initial encounter with the immune system is poorly understood. Here we propose a new model for how these proteins can initiate autoimmunity. We found that rat and human pancreatic islets release the intracellular β-cell autoantigens in human T1D, GAD65, IA-2, and proinsulin in exosomes, which are ...