Publicaties
Geographic differences in the contribution of ubiA mutations to high-level ethambutol resistance in mycobacterium tuberculosis Universiteit Antwerpen
Optimization of a reversed-phase high-performance thin-layer chromatography method for the separation of isoniazid, ethambutol, rifampicin and pyrazinamide in fixed-dose combination antituberculose tablets Vrije Universiteit Brussel
Efficacy and safety of a 4-drug fixed-dose combination regimen compared with separate drugs for treatment of pulmonary tuberculosis: the Study C randomized controlled trial Instituut voor Tropische Geneeskunde
A four-month gatifloxacin-containing regimen for treating tuberculosis Instituut voor Tropische Geneeskunde
BACKGROUND: Shortening the course of treatment for tuberculosis would be a major improvement for case management and disease control. This phase 3 trial assessed the efficacy and safety of a 4-month gatifloxacin-containing regimen for treating rifampin-sensitive pulmonary tuberculosis.
METHODS: We conducted a noninferiority, randomized, open-label, controlled trial involving patients 18 to 65 years of age with smear-positive, ...
Performance of microscopic observation drug susceptibility for the rapid diagnosis of tuberculosis and detection of drug resistance in Bamako, Mali Instituut voor Tropische Geneeskunde
Objectives: In Mali early detection and treatment of multidrug-resistant tuberculosis MDR-TB) are still challenging due to the cost, time and/or complexity associated with regular tests. Microscopic Observation Drug Susceptibility MODS) is a low-cost assay validated by WHO in 2010. It is a liquid-culture-based assay to detect the 'cording' characteristic of Mycobacterium tuberculosis complex and to assess susceptibility to both isoniazid and ...