Het benutten van de methylerythritolfosfaatroute als een bron van medicijndoelen voor nieuwe anti-infectiva Universiteit Gent
Anti-infective resistance is a serious global healthcare issue, calling for the development of compounds with a novel mode of action. An interdisciplinary approach will afford potent and selective inhibitors of the underexplored methylerythritol phosphate pathway, a rich source of targets that are essential for medically relevant pathogens such as the causative agents of malaria and tuberculosis. The discovery of anti-infective agents ...