Detailed efficiency analysis of columns with a different packing quality and confirmation via total pore blocking Vrije Universiteit Brussel
We report on a systematic study involving columns with a clearly different efficiency (4 distinct quality groups) obtained by packing the columns that were C-18 bonded and endcapped with a different carbon loading. Using B-term analysis (via peak parking) and theoretical models to estimate the magnitude of the C-m- and C-s-term contributions, it could be concluded that the difference in efficiency among the groups was entirely due to a ...