Publicaties
Successful ECT treatment after relapse during VNS therapy Vrije Universiteit Brussel
We present a case of a patient with severe treatment resistant depression who relapsed while being treated with vagus nerve stimulation. We describe that he was safely treated with unilateral ECT concomitantly with the VNS.
HF-rTMS treatment in medication-resistant melancholic depression: results from 18FDG-PET brain imaging. Vrije Universiteit Brussel
OBJECTIVE: In this open study, we evaluate whether a favorable HF-rTMS treatment outcome could be predicted by baseline prefrontal brain glucose metabolism (CMRglc), measured by 18fluorodeoxyglucose ...
Accelerated Repetitive Transcranial Magnetic Stimulation to Treat Major Depression Vrije Universiteit Brussel
Repetitive transcranial magnetic stimulation (rTMS) is an effective and evidence-based therapy for treatment-resistant major depressive disorder. A conventional course of rTMS applies 20-30 daily sessions over 4-6 weeks. The schedule of rTMS delivery can be accelerated by applying multiple stimulation sessions per day, which reduces the duration of a treatment course with a predefined number of sessions. Accelerated rTMS reduces time demands, ...
EEG connectivity between the subgenual anterior cingulate and prefrontal cortices in response to antidepressant medication Vrije Universiteit Brussel Universiteit Gent
Antidepressant medication is the most common treatment for major depressive disorder (MDD), however, the precise working mechanism underlying these treatments remains unclear. Recent neuromodulation treatments demonstrate that direct stimulation of the dorsolateral prefrontal cortex (DLPFC), dorsomedial prefrontal cortex (DMPFC), and subgenual anterior cingulate (sgACC) relate to clinical improvement, suggesting connectivity alterations of ...
Pharmacotherapy and nutritional supplements for seasonal affective disorders Vrije Universiteit Brussel Universiteit Antwerpen
INTRODUCTION: A seasonal affective disorder (SAD) is a subtype of unipolar and bipolar major depressive disorders. It is characterized by its annual recurrence of depressive episodes at a particular season, mostly seen in winter and is responsible for 10-20% of the prevalence of major depressive disorders. Some pathophysiological hypotheses, such as the phase delay and the monoamine depletion hypotheses, have been postulated but the exact ...