Publicaties
Episodic vestibular symptoms in children with a congenital cytomegalovirus infection Universiteit Gent
De novo thrombotic microangiopathy induced by cytomegalovirus infection leading to renal allograft loss Universiteit Gent
Brain MRI findings in newborns with congenital cytomegalovirus infection : results from a large cohort study Universiteit Gent
Risk Factors for hearing loss at birth in newborns with congenital cytomegalovirus infection Universiteit Gent Universiteit Antwerpen
The seroprevalence of cytomegalovirus infection in Belgium anno 2002 and 2006: a comparative analysis with hepatitis A virus seroprevalence Instituut voor Tropische Geneeskunde Universiteit Gent Universiteit Hasselt Universiteit Antwerpen
Cytomegalovirus (CMV) infection is endemic worldwide but its seroprevalence varies widely. The goal of this study was to estimate the age-specific seroprevalence of CMV infection in Belgium based on two cross-sectional serological datasets from 2002 and 2006. The seroprevalence was estimated relying on diagnostic test results based on cut-off values pre-specified by the manufacturers of the tests as well as relying on mixture models applied ...
Public health impact of congenital toxoplasmosis and cytomegalovirus infection in Belgium, 2013 Instituut voor Tropische Geneeskunde Universiteit Hasselt Universiteit Gent Universiteit Antwerpen
Congenital toxoplasmosis (CT) and cytomegalovirus infection (cCMV) may cause significant morbidity and even fetal or neonatal mortality. We aimed to quantify the disease burden of CT and cCMV in Belgium in terms of disability-adjusted life years (DALYs) and identify data gaps. The public health impact of CT and cCMV in Belgium in 2013 was 188 (95% uncertainty interval [UI], 43-419) and 1976 (95% UI, 757-4067) DALYs, respectively. The major ...
Prospective multicenter comparison of urine culture with PCR on dried blood spots using 2 different extraction and PCR methods in neonates suspected for congenital cytomegalovirus infection Instituut voor Tropische Geneeskunde Universiteit Gent KU Leuven Universiteit Antwerpen
To evaluate the potential of dried blood spots (DBS) as a congenital cytomegalovirus (cCMV) testing specimen, the laboratory diagnostic accuracy of polymerase chain reaction (PCR) on DBS was compared to viral urine cultures from neonates suspected for cCMV. Two different extraction methods (EasyMAG, bioMerieux versus Qiagen) and 2 real-time PCR protocols (in-house versus Argene) were compared. We were able to collect both DBS and urine ...
Risk factors for and clinical outcome of congenital cytomegalovirus infection in a peri-urban West-African birth cohort Instituut voor Tropische Geneeskunde
BACKGROUND: Congenital cytomegalovirus (CMV) infection is the most prevalent congenital infection worldwide. Epidemiology and clinical outcomes are known to vary with socio-economic background, but few data are available from developing countries, where the overall burden of infectious diseases is frequently high.
METHODOLOGY/PRINCIPAL FINDINGS: As part of an ongoing birth cohort study in The Gambia among term infants, urine samples ...
Disease burden of congenital cytomegalovirus infection at school entry age: study design, participation rate and birth prevalence Instituut voor Tropische Geneeskunde
Congenital cytomegalovirus infection (cCMV) may lead to symptoms at birth and long-term consequences. We present a nationwide, retrospective cohort study on the outcome of cCMV up to age 6 years. For this study we identified cCMV, using polymerase chain reaction, by analysing dried blood spots, which are taken shortly after birth for neonatal screening. The group of children with cCMV were compared to a group of children who were cCMV ...