Publicaties

Huntington's disease (HD) is a progressive neurodegenerative disease affecting motor and cognitive abilities. Multiple studies have found white matter anomalies in HD-affected humans and animal models of HD. The identification of sensitive white-matter-based biomarkers in HD animal models will be important in understanding disease mechanisms and testing the efficacy of therapeutic interventions. Here we investigated the progression of white ...

A wide range of porcelain-based materials is composed of quartz crystalline particles dispersed in a homogeneous glassy phase. During the cooling stage these composites are subjected to stresses related to the transition from β to α quartz at 573 °C. This work studies, numerically and experimentally, the influence of the cooling rate, the quantity, and the size of the quartz crystalline particles on the stresses suffered by the material ...

Since the 1970s, it is empirically known that the area of solar coronal holes affects the properties of high-speed solar wind streams (HSSs) at Earth. We derive a simple analytical model for the propagation of HSSs from the Sun to Earth, and thereby show how the area of coronal holes and the size of their boundary regions affect the HSS velocity, temperature, and density near Earth. We presume that velocity, temperature, and density profiles ...

In the Arusha volcanic region in northern Tanzania, within the eastern branch of the East African Rift System, water shortage is common and much of the surface water and groundwater contain fluoride (F⁻) concentration above the WHO limit (1.5 mg/L) recommended for drinking water. The groundwater is the main source of drinking water in the area. Prolonged intake of this high F⁻ water has caused dental and skeletal fluorosis among the local ...

Since the discovery of the Higgs boson in 2012, detailed studies of its properties have been ongoing. Besides its mass, its width-related to its lifetime-is an important parameter. One way to determine this quantity is to measure its off-shell production, where the Higgs boson mass is far away from its nominal value, and relating it to its on-shell production, where the mass is close to the nominal value. Here we report evidence for such ...

Human hair absorbs numerous biomolecules from the body during its growth. This can act as a fingerprint to determine substance intake of an individual, which can be useful in forensic studies. The cocaine concentration profile along the growth axis of hair indicates the time evolution of the metabolic incorporation of cocaine usage. It could be either assessed by chemical extraction and further analysis of hair bundels, or by direct single hair ...

Rembrandt’s Aristotle with a Bust of Homer was examined and analysed to investigate the origin of a disfiguring hazy bloom, most visible in the dark paint passages that had been developing in the painting for decades. By combining the results of macro X-ray fluorescence imaging and the re-examination of photographic documentation, X-radiographs, autoradiographs and cross-section paint samples taken in earlier studies, the deterioration is ...

The impact of graphene reinforcement on the mechanical properties of metals has been a subject of intense investigation over the last decade in surface applications to mitigate the impact of tribological loadings or for strengthening purposes when dispersed into a bulk material. Here, the effect on the plastic indentation response of a single graphene layer grown on copper is analyzed for two configurations: one with graphene at the surface, the ...

The relationship between the peak velocities of high-speed solar wind streams near Earth and the areas of their solar source regions, i.e., coronal holes, is known since the 1970s, but still physically not well understood. We perform 3D MHD simulations us- ing the EUHFORIA code to show that this empirical relationship forms during the propagation phase of high-speed streams from the Sun to Earth. For this purpose, we neglect the acceleration ...

This study aims to estimate crack location and crack length in damaged beam structures using transfer matrix formulations, which are based on analytical solutions of governing equations of motion. A single variable shear deformation theory (SVSDT) that considers parabolic shear stress distribution along beam cross-section is used, as well as, Timoshenko beam theory (TBT). The cracks are modelled using massless rotational springs that divide ...