Mechanobiologische optimalisatie van regeneratie in celverrijkte constructimplantaten in degeneratief kraakbeen: een defectherstelmethode door het herstellen van energieabsorptie KU Leuven
Knee cartilage defects and consequent degeneration contribute to the development of osteoarthritis (OA). OA affects the mechanical integrity of the tissue, whose main function is to absorb shock and minimize peak loads in the underlying subchondral bone.
Tissue engineering methods propose solutions to OA by implanting chondrocyte cell-enriched hydrogel/scaffold constructs within degenerative cartilage defects. By applying mechanical ...