Publicaties

1 - 10 of 12 resultaten

Sorteren op
Zoek term:

Improving care in the older and/or cardiac surgical patient. KU Leuven

Danny Hoogma
Aging is a complex process that is accompanied by diminishing physiological reserves resulting in a decreased tolerance for stressors, which is considered the basis for frailty. The demographic evolution of the population in the Western world, in conjunction with the increased incidence of cardiovascular disease, has resulted in a significant increase in older persons requiring cardiac surgery. In addition, the older surgical population ...

Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT) Vrije Universiteit Brussel

Bjørn Erik Neerland, Rolf Busund, Rune Haaverstad, Jorunn L Helbostad, Svein Aslak Landsverk, Ieva Martinaityte, Hilde Margrethe Norum, Johan Ræder, Geir Selbaek, Melanie R Simpson, et al.

INTRODUCTION: Postoperative delirium is common in older cardiac surgery patients and associated with negative short-term and long-term outcomes. The alpha-2-adrenergic receptor agonist dexmedetomidine shows promise as prophylaxis and treatment for delirium in intensive care units (ICU) and postoperative settings. Clonidine has similar pharmacological properties and can be administered both parenterally and orally. We aim to study whether ...

Case-control study on the interplay between immunoparalysis and delirium after cardiac surgery Vrije Universiteit Brussel

Shokoufeh CheheiliSobbi, Annemieke M Peters van Ton, Esther M Wesselink, Marjolein F Looije, Jelle Gerretsen, Wim J Morshuis, Arjen Slooter, Wilson F Abdo, Peter Pickkers, Mark van den Boogaard, et al.

BACKGROUND: Delirium occurs frequently following cardiothoracic surgery, and infectious disease is an important risk factor for delirium. Surgery and cardiopulmonary bypass induce suppression of the immune response known as immunoparalysis. We aimed to investigate whether delirious patients had more pronounced immunoparalysis following cardiothoracic surgery than patients without delirium, to explain this delirium-infection association.

...

Position paper concerning the competence, performance and environment required for the practice of ablation in children and in congenital heart disease Vrije Universiteit Brussel

Philippe Maury, Jean Benoit Thambo, Alice Maltret, Nicolas Combes, Sébastien Hascoet, Nicolas Derval, Magalie Ladouceur, Philippe Acar, Pascal Amedro, Frederic Anselm, et al.

The population of patients with congenital heart disease (CHD) is continuously increasing, and a significant proportion of these patients will experience arrhythmias because of the underlying congenital heart defect itself or as a consequence of interventional or surgical treatment. Arrhythmias are a leading cause of mortality, morbidity and impaired quality of life in adults with CHD. Arrhythmias may also occur in children with or without ...

Hallucinations after Cardiac Surgery Vrije Universiteit Brussel

Thomas H Ottens, Iris E C Sommer, Marieke J Begemann, Maya J L Schutte, Maarten Jan Cramer, Willem J Suyker, Diederik van Dijk, Arjen Slooter

Background and Objective: Hallucinations after cardiac surgery can be a burden, but their prevalence and phenomenology have not been studied well. Risk factors for postoperative hallucinations, as well as their relation to delirium are unclear. We aimed to study the prevalence and phenomenology of hallucinations after cardiac surgery, and to study the association between hallucinations and delirium in this population. Materials and Methods: ...

Position paper concerning the competence, performance and environment required in the practice of complex ablation procedures Vrije Universiteit Brussel

Philippe Maury, Pascal Defaye, Didier Klug, Christine Alonso, Frederic Anselme, Laurent Fauchier, Estelle Gandjbakhch, Daniel Gras, Jean Sylvain Hermida, Gabriel Laurent, et al.

The introduction of catheter ablation techniques has vastly improved the treatment of cardiac arrhythmias. However, as complex ablations are technically demanding and can cause various complications, they require a high level of expertise to maximize success rates and minimize complication rates. As French recommendations regarding the required technical competence and equipment are not yet available, this position paper has been compiled by ...

Recent advances in devices for vagus nerve stimulation Universiteit Gent

Ann Mertens, Robrecht Raedt, Stefanie Gadeyne, Evelien Carrette, Paul Boon
Introduction: Vagus nerve stimulation (VNS) has become a valuable treatment option for refractory epilepsy and depression. To improve clinical efficacy and minimize side effects, novel device technology for VNS is under development and investigation.Areas covered: For epilepsy, the AspireSR (R), and SenTiva VNS therapy systems are the two most recently developed VNS devices. These novel devices have implemented a closed-loop approach and contain ...

Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries Vrije Universiteit Brussel KU Leuven

Teeba Ibraheem Ahmad, A. Hoeft, P Holt, Rupert M Pearse
Background
As global initiatives increase patient access to surgical treatments, there remains a need to understand the adverse effects of surgery and define appropriate levels of perioperative care.

Methods
We designed a prospective international 7-day cohort study of outcomes following elective adult inpatient surgery in 27 countries. The primary outcome was in-hospital complications. Secondary outcomes were death ...

Late recovery of atrioventricular conduction after postsurgical chronic atrioventricular block is not exceptional KU Leuven

Rik Willems, Filip Rega, Marc Gewillig
OBJECTIVE: Postsurgical atrioventricular block may complicate surgery for congenital heart defects and is generally considered permanent when persisting longer than 14 days after surgery. In this study, we evaluate the occurrence of spontaneous late recovery of atrioventricular conduction in postsurgical chronic atrioventricular block and discuss its clinical implications. METHODS: We retrospectively reviewed all cardiac surgical procedures on ...

Safe single-dose administration of propofol in patients with established Brugada syndrome Universiteit Antwerpen KU Leuven

Panagiotis Flamee, Carlo De Asmundis, Jigme T. Bhutia, Giulio Conte, Stefan Beckers, Vincent Umbrain, Christian Verborgh, Gian-Battista Chierchia, Sophie Van Malderen, Ruben Casado-Arroyo, et al.
BackgroundPropofol is an anesthetic drug with a very attractive pharmacokinetic profile, which makes it the induction agent of choice, especially in day-case surgery. Data on its potential proarrhythmic effects in patients with Brugada syndrome (BS) patients are still lacking. The aim of our study was to investigate whether a single dose of propofol triggered any adverse events in consecutive high-risk patients with BS. MethodsAll consecutive ...