Publicaties
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The optimal timing for imaging brain tumours and other brain lesions with 18F-labelled fluoromethylcholine: a dynamic positron emission tomography study Universiteit Gent
Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood brain barrier permeability Vrije Universiteit Brussel
Aims: The cytoplasmic calcium concentration ([Ca2+]i) is an important factor determining the permeability of endothelial cell layers but little is known on the effect of [Ca2+]i dynamics on endothelial function. Here, we applied several conditions that trigger [Ca2+]i oscillations and cell-to-cell propagating Ca2+ waves, and determined the involvement of connexin channels and consequent effects on endothelial barrier function, in model systems ...
The European Academy of Neurology brain health strategy : one brain, one life, one approach Universiteit Gent
Hypofractionated frameless stereotactic intensity-modulated radiotherapy with whole brain radiotherapy for the treatment of 1-3 brain metastases Universiteit Gent
Assessment of brain age in posttraumatic stress disorder : findings from the ENIGMA PTSD and brain age working groups Universiteit Gent
Background Posttraumatic stress disorder (PTSD) is associated with markers of accelerated aging. Estimates of brain age, compared to chronological age, may clarify the effects of PTSD on the brain and may inform treatment approaches targeting the neurobiology of aging in the context of PTSD. Method Adult subjects (N = 2229; 56.2% male) aged 18-69 years (mean = 35.6, SD = 11.0) from 21 ENIGMA-PGC PTSD sites underwent T1-weighted brain structural ...
Ageing and brain plasticity. Training-induced alterations in spectral power of the brain and motor coordination KU Leuven
Declines in sensorimotor and cognitive function are well-known consequences of ageing. Improving our understanding of what ageing entails at cellular up to systemic levels is hence timely and urgent. And, finding strategies to decelerate or even reverse the pervasive effects of aging can have a major societal impact. The aim of this thesis was to investigate changes in spectral dynamics of the brain associated with bimanual task difficulty, ...