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Computational strategies and challenges for using native ion mobility mass spectrometry in biophysics and structural biology Universiteit Antwerpen
Native mass spectrometry (MS) allows the interrogation of structural aspects of macromolecules in the gas phase, under the premise of having initially maintained their solution-phase noncovalent interactions intact. In the more than 25 years since the first reports, the utility of native MS has become well established in the structural biology community. The experimental and technological advances during this time have been rapid, resulting in ...
Biophysics and Physiology of the Volume-Regulated Anion Channel (VRAC)/Volume-Sensitive Outwardly Rectifying Anion Channel (VSOR) KU Leuven
The volume-regulated anion channel (VRAC), also known as the volume-sensitive outwardly rectifying (VSOR) anion channel or the volume-sensitive organic osmolyte/anion channel (VSOAC), is essential for cell volume regulation after swelling in most vertebrate cell types studied to date. In addition to its role in cell volume homeostasis, VRAC has been implicated in numerous other physiological and pathophysiological processes, including cancer, ...
Materials science and biophysics applications at the ISOLDE radioactive ion beam facility KU Leuven
The ISOLDE isotope separator facility at CERN provides a variety of radioactive ion beams, currently more than 800 different isotopes from ∼70 chemical elements. The radioisotopes are produced on-line by nuclear reactions from a 1.4 GeV proton beam with various types of targets, outdiffusion of the reaction products and, if possible, chemically selective ionisation, followed by 60 kV acceleration and mass separation. While ISOLDE is mainly used ...
Statistical biophysics of hematopoiesis and growing cell populations Vrije Universiteit Brussel
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Updated common biophysical criteria to define natural constraints for agriculture in Europe: Definition and scientific justification for the common biophysical criteria and Technical Factsheets KU Leuven
A panel of soil, climate and land evaluation experts reviewed a set of land evaluation methods in order to elaborate an approach which can support the identification of severe natural constraints to agriculture in the EU28. The driver for this exercise is Article 50.3 of EC-Regulation 1698/2005 calling for the revision of the existing system based on criteria related to low soil productivity and poor climate conditions for agriculture and the ...
Biophysical characterization of proteoliposomes harboring AnxA5 and application in biomineralization KU Leuven
Annexin V effects in biophysical properties of lipid membranes probed by fluorescence spectroscopy KU Leuven
Biophysical aspects of biomineralization KU Leuven
© 2017, International Union for Pure and Applied Biophysics (IUPAB) and Springer-Verlag GmbH Germany. During the process of endochondral bone formation, chondrocytes and osteoblasts mineralize their extracellular matrix (ECM) by promoting the synthesis of hydroxyapatite (HA) seed crystals in the sheltered interior of membrane-limited matrix vesicles (MVs). Several lipid and proteins present in the membrane of the MVs mediate the interactions of ...