Replication Data for: ‘Novel Human/Non-Human Primate Cross-Reactive Anti-Transferrin Receptor Nanobodies for Brain Delivery of Biologics‘ KU Leuven
This dataset contains raw data contributing to the publication ‘Novel Human/Non-Human Primate Cross-Reactive Anti-Transferrin Receptor Nanobodies for Brain Delivery of Biologics‘. This publication is about the discovery of nanobodies (variable domain of camelid heavy chain-only antibodies) binding both human and non-human primate transferrin receptor (TfR) that could serve as moieties to improve brain permeability of therapeutic antibodies. The blood-brain barrier (BBB), while being the gatekeeper of the central nervous system (CNS), is a bottleneck for the treatment of neurological diseases, ...