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Influence of microplastic-associated biofilms on the bioavailability of a mixture of cadmium and benzo[a]pyrene by the analysis of biomarker gene expression in larval zebrafish Vlaams Instituut voor de Zee
Microplastics (MPs, 1 µm – 5 mm) in aquatic environments undergo complex weathering transformations such as those induced by microbial colonization and biofilm formation, that affect their ability to interact with environmental contaminants (co-contaminants). In this study, the microbial composition of MP biofilms and its influence on the sorption and bioavailability of two co-contaminants with different physicochemistry, benzo[a]pyrene (B[a]P) ...
New Immunochemically-based Field Test for Monitoring Benzo[a]pyrene in Aqueous Samples Universiteit Gent
Polycyclic aromatic hydrocarbons (PAHs) represent health and environmental concerns. The present study was designed to develop a highly sensitive and reliable immunochemically-based non-in stru mental field assay to monitor the presence of benzo[a]pyrene (BAP) in aqueous samples at the ppt-level using visible test evaluation. The corresponding gel-based immunoassay was set up to combine preconcentration and detection of the target analyte using ...
A common carcinogen benzo[a]pyrene causes neuronal death in mouse via microglial activation KU Leuven
BACKGROUND: Benzo[a]pyrene (B[a]P) belongs to a class of polycyclic aromatic hydrocarbons that serve as micropollutants in the environment. B[a]P has been reported as a probable carcinogen in humans. Exposure to B[a]P can take place by ingestion of contaminated (especially grilled, roasted or smoked) food or water, or inhalation of polluted air. There are reports available that also suggests neurotoxicity as a result of B[a]P exposure, but the ...
Insight into the transgenerational effect of benzo[a]pyrene on bone formation in a teleost fish (Oryzias latipes) Universiteit Gent
A luminescence immunoassay test method for determining benzo[a]pyrene in natural water Universiteit Gent
Effects of microplastics alone and with adsorbed benzo(a)pyrene on the gills proteome of **Scrobicularia plana** Universiteit Antwerpen
Microplastics (MPs) are globally present in the marine environment, but the biological effects on marine organisms at the molecular and cellular levels remain scarce. Due to their lipophilic nature, MPs can adsorb other contaminants present in the marine environment, which may increase their detrimental effects once ingested by organisms. This study investigates the effects of low-density polyethylene (PE) MPs with and without adsorbed ...
Capacitive sensor for detection of benzo(a)pyrene in water Universiteit Gent
Influence of particle size on ecotoxicity of low-density polyethylene microplastics, with and without adsorbed benzo-a-pyrene, in clam **Scrobicularia plana** Universiteit Antwerpen
This study investigated the ecotoxicological effects of differently sized (4-6 mu m and 20-25 mu m) low-density polyethylene (LDPE) microplastics (MPs), with and without adsorbed benzo-a-pyrene (BaP), in clam Scrobicularia plana. Biomarkers of oxidative stress (superoxide dismutase-SOD; catalase-CAT), biotransformation (glutathione-S-transferases-GST), oxidative damage (lipid peroxidation-LPO) and neurotoxicity (acetylcholinesterase-AChE) were ...
Benzo[a]pyrene-induced cell cycle arrest in HepG2 cells is associated with delayed induction of mitotic instability Vrije Universiteit Brussel
The environmental carcinogen benzo[a]pyrene (B[a]P) after being metabolised by cytochrome P450 enzymes forms DNA adducts. This abnormal situation induces changes in the cell cycle, DNA damage, chromosomal and mitotic aberrations, all of which may be related to carcinogenesis. In order to further investigate the mechanistic basis of these effects, HepG2 cells were treated with 3 ?M B[a]P for various time periods, followed by further incubation in ...