Requirements for Automation of the Human Micronucleus Cytome Assay for High Throughput Analysis Vrije Universiteit Brussel
Analysis of micronuclei (MN) is widely used for human biomonitoring or in vitro/in vivo genotoxicity testing, and provides a sensitive and relatively easy method to assess genetic damage. The fact that baseline MN frequencies in cytokinesis-blocked (CB) lymphocytes have been shown to be a predictive biomarker for cancer risk strengthens the importance of the CBMN assay as a reliable method for human biomonitoring of early genetic effects. We ...