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Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium KU Leuven
A genome-wide association study (GWAS) identified single-nucleotide polymorphisms (SNPs) at 1p11.2 and 14q24.1 (RAD51L1) as breast cancer susceptibility loci. The initial GWAS suggested stronger effects for both loci for estrogen receptor (ER)-positive tumors. Using data from the Breast Cancer Association Consortium (BCAC), we sought to determine whether risks differ by ER, progesterone receptor (PR), human epidermal growth factor receptor 2 ...
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the breast cancer association consortium studies KU Leuven
Background Previous studies have suggested that breast cancer risk factors are associated with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors. Methods We pooled tumor marker and epidemiological risk factor data from 35 568 invasive breast cancer case patients from 34 studies participating in the Breast Cancer Association Consortium. Logistic regression models were used in case-case analyses to estimate ...
Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium Vlaams Instituut voor Biotechnologie KU Leuven
Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the Breast Cancer Association Consortium: a combined case-control study KU Leuven
ABSTRACT: INTRODUCTION: Several common breast cancer genetic susceptibility variants have recently been identified. We aimed to determine how these variants combine with a subset of other known risk factors to influence breast cancer risk in white women of European ancestry using case-control studies participating in the Breast Cancer Association Consortium. METHODS: We evaluated two-way interactions between each of age at menarche, ever having ...
Association Membership and Generalised Trust: are connections between Associations losing their Value ? Vrije Universiteit Brussel
Guilt by association and honor by association: The role of acquired equivalence KU Leuven
Guilt by association and honor by association are two types of judgments that suggest that a negative or positive quality of a person or object can transfer to another person or object, merely by co-occurrence. Most examples have been demonstrated under conditions of direct associations. Here, we provide experimental evidence of guilt by association and honor by association via indirect associations. We show that participants may treat two ...
Dissociations and associations between shape and category representations in the two visual pathways KU Leuven
The dorsal and ventral visual pathways represent both visual and conceptual object properties. Yet the relative contribution of these two factors in the representational content of visual areas is unclear. Indeed, research investigating brain category representations rarely dissociate visual and semantic properties of objects. We present a human event-related fMRI study with a two-factorial stimulus set with 54 images that explicitly dissociates ...
On the assimilation of instructions : stimulus-response associations are implemented but not stimulus-task associations Universiteit Gent
The assimilation of instructions consists of two stages. First, a task model is formed on the basis of instructions. Second, this model is implemented, resulting in highly accessible representations, which enable reflexive behavior that guides the application of instructions. Research frequently demonstrated that instructions can lead to automatic response activation, which indicates that stimulus-response associations can be implemented on the ...