Publicaties
Targeting Cellular Cofactors in HIV Therapy KU Leuven
Reported consent processes and demographics Instituut voor Tropische Geneeskunde
OBJECTIVES: Efforts are needed to improve informed consent of participants in research. The Strategic Timing of AntiRetroviral Therapy (START) study provides a unique opportunity to study the effect of length and complexity of informed consent documents on understanding and satisfaction among geographically diverse participants.
METHODS: Interested START sites were randomized to use either the standard consent form or the concise ...
Community ART support groups in Mozambique: the potential of patients as partners in care Instituut voor Tropische Geneeskunde
BACKGROUND: High rates of attrition are stymying Mozambique's national HIV Program's efforts to achieve 80% treatment coverage. In response, Mozambique implemented a national pilot of Community Adherence and Support Groups (CASG). CASG is a model in which antiretroviral therapy (ART) patients form groups of up to six patients. On a rotating basis one CASG group member collects ART medications at the health facility for all group members, and ...
Prevalence of drug resistance mutations among ART-naive and -experienced HIV-infected patients in Sierra Leone Vrije Universiteit Brussel
OBJECTIVES: The aim of this study was to assess the prevalence of HIV drug resistance (HIVDR) in HIV-infected ART-naive and -experienced patients in Sierra Leone.
PATIENTS AND METHODS: We conducted a cross-sectional study of HIV-positive adults aged ≥18 years at Connaught Hospital in Freetown, Sierra Leone in November 2017. Sequencing was performed in the reverse transcriptase, protease and integrase regions, and interpreted using the ...
Cascade of care for HIV-seroconverters in rural Tanzania: a longitudinal study Instituut voor Tropische Geneeskunde
Advanced HIV disease at enrolment in HIV care Instituut voor Tropische Geneeskunde
BACKGROUND: Early HIV diagnosis and enrolment in care is needed to achieve early antiretroviral treatment (ART) initiation. Studies on HIV disease stage at enrolment in care from Asian countries are limited. We evaluated trends in and factors associated with late HIV disease presentation over a ten-year period in the largest ART center in Cambodia.
METHODS: We conducted a retrospective analysis of program data including all ARV-naïve ...
Long-term use of darunavir/ritonavir-containing regimens in daily practice in Belgium: retrospective observational cohort data of 1701 HIV-patients Instituut voor Tropische Geneeskunde Universiteit Gent KU Leuven
Background Once daily (QD) ritonavir or cobicistat-boosted darunavir (DRV/b), in combination with other antiretrovirals (ARVs), is recommended as a first-line option for human immunodeficiency virus-infected patients in European and USA guidelines. The objective of this study was to analyse the outcomes of DRV/r QD-based antiretroviral therapy (ART) regimens in real-life settings.Methods This is an observational, non-interventional, ...
Virologic suppression and associated factors in HIV infected Ugandan female sex workers: a cross-sectional study Universiteit Hasselt
Any impact of blips and low-level viraemia episodes among HIV-infected patients with sustained virological suppression on ART? Vrije Universiteit Brussel
OBJECTIVES: The objective of this study was to evaluate the prevalence of blips and risk of virological failure (VF) among HIV-infected patients with sustained virological suppression (HIV-RNA <50 copies/mL) on ART.
METHODS: Newly diagnosed (2004-13) HIV-infected patients with sustained virological suppression on ART (minimum follow-up of 3 months) were identified. Risk of VF was evaluated according to different plasma HIV-RNA ...