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Computational models of sprouting angiogenesis and cell migration: towards multiscale mechanochemical models of angiogenesis KU Leuven
Angiogenesis, the formation of new bloods vessels from the existing vasculature, is a process that is essential during development and regeneration of tissues, and that plays a major role in diseases like cancer. Computational models have been designed to obtain a better understanding of the mechanisms behind angiogenesis. In this paper we review computational models of sprouting angiogenesis. These models can be subdivided into three ...
Techniques used to assess intussusceptive angiogenesis : a systematic review Universiteit Gent
Intussusceptive angiogenesis (IA) is an important physiological form of angiogenesis in which an existing vessel splits in two by the formation of an intraluminal tissue pillar. The presence of these intraluminal pillars form the hallmark of ongoing IA in growing vascular beds. However, their visualization is technically challenging. The goal of this systematic review was to investigate which techniques are being used to identify intraluminal ...
The impact of endothelial cells proliferation in a multiscale realistic reproduction of angiogenesis Universiteit Gent
Angiogenesis is a biological process in which new capillaries form from pre-existing vessels and it plays a key role in the several fatal diseases like cancer. Principally, the extension of angiogenic sprouts depends on migration and proliferation of endothelial cells (ECs). Multiple experimental and computational studies of angiogenesis have investigated the ECs dynamics so far, however, despite the importance of cellular proliferation, the ...
Mesenchymal stem/stromal cells as a pharmacological and therapeutic approach to accelerate angiogenesis Universiteit Hasselt
Mesenchymal stem cells or multipotent stromal cells (MSCs) have initially captured attention in the scientific world because of their differentiation potential into osteoblasts, chondroblasts and adipocytes and possible transdifferentiation into neurons, glial cells and endothelial cells. This broad plasticity was originally hypothesized as the key mechanism of their demonstrated efficacy in numerous animal models of disease as well as in ...
Estrogens regulate placental angiogenesis in horses Universiteit Gent
Evaluation of angiogenesis in an acellular porous biomaterial based on polyhydroxybutyrate and chitosan using the chicken ex ovo chorioallantoic membrane model Universiteit Gent
Simple Summary The chorioallantoic membrane (CAM) is an avian extraembryonic membrane widely used as an experimental assay to study angiogenesis and its inhibition in response to tissues, cells, or soluble factors. In recent years, the CAM has become popular in scientific studies focused on the use of its potential for the study of biocompatibility of materials for regenerative strategies and tissue engineering applications. Great research ...