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Air pollution and the fetal origin of disease: A systematic review of the molecular signatures of air pollution exposure in human placenta KU Leuven

Leen J Luyten, Nelly D Saenen, Bram G Janssen, Karen Vrijens, Michelle Plusquin, Harry A Roels, Florence Debacq-Chainiaux, Tim Nawrot
BACKGROUND: Fetal development is a crucial window of susceptibility in which exposure-related alterations can be induced on the molecular level, leading to potential changes in metabolism and development. The placenta serves as a gatekeeper between mother and fetus, and is in contact with environmental stressors throughout pregnancy. This makes the placenta as a temporary organ an informative non-invasive matrix suitable to investigate ...

Cardiorespiratory effects of physical activity and urban air pollution in Europe Universiteit Hasselt

Michelle LAEREMANS
Each year, five million premature deaths are due to a lack of physical activity. Active mobility (i.e. walking and cycling as a means of transport) has been introduced as an accessible solution to increase daily physical activity levels because it may be easier to integrate into daily routines compared to sports and exercise. The PASTA project (Physical Activity through Sustainable Transport Approaches) studied the benefits and risks of active ...

Concern over health effects of air pollution is associated to NO2 in seven European cities Universiteit Hasselt

Evi DONS, Michelle LAEREMANS, Esther Anaya-Boig, Ione Avila-Palencia, Christian Brand, Audrey de Nazelle, Mailin Gaupp-Berghausen, Thomas Gotschi, Mark Nieuwenhuijsen, Juan Pablo Orjuela, et al.
Subjective perception of air pollution is important and can have impacts on health in its own rights, can lead to protective behaviour, or it can be leveraged to engage citizens and stakeholders in support of cleaner air policies. The aim of the current analysis was to examine associations between level of concern over health effects of air pollution and personal and environmental factors. In seven European cities, 7622 adult participants were ...

Immune biomarkers link air pollution exposure to blood pressure in adolescents KU Leuven

Mary Prunicki, Nicholas Cauwenberghs, Jennifer Arthur Ataam, Hesam Movassagh, Juyong Brian Kim, Tatiana Kouznetsova, Joseph C Wu, Holden Maecker, Francois Haddad, Kari Nadeau, et al.
BACKGROUND: Childhood exposure to air pollution contributes to cardiovascular disease in adulthood. Immune and oxidative stress disturbances might mediate the effects of air pollution on the cardiovascular system, but the underlying mechanisms are poorly understood in adolescents. Therefore, we aimed to identify immune biomarkers linking air pollution exposure and blood pressure levels in adolescents. METHODS: We randomly recruited 100 ...

Cardiovascular effects of air pollution Vrije Universiteit Brussel

Jean-François Argacha

Air pollution is composed of particulate matter (PM) and gaseous pollutants, such as nitrogen dioxide and ozone. PM is classified according to size into coarse particles (PM 10), fine particles (PM 2.5) and ultrafine particles. We aim to provide an original review of the scientific evidence from epidemiological and experimental studies examining the cardiovascular effects of outdoor air pollution. Pooled ...

Long-term low-level ambient air pollution exposure and risk of lung cancer – A pooled analysis of 7 European cohorts Vrije Universiteit Brussel

Ulla Arthur Hvidtfeldt, Gianluca Severi, Zorana Jovanovic Andersen, Richard Atkinson, Mariska Bauwelinck, Tom Bellander, Marie Christine Boutron-Ruault, Jørgen Brandt, Bert Brunekreef, Giulia Cesaroni, et al.

Background/aim: Ambient air pollution has been associated with lung cancer, but the shape of the exposure-response function - especially at low exposure levels - is not well described. The aim of this study was to address the relationship between long-term low-level air pollution exposure and lung cancer incidence.

Methods: The “Effects of Low-level Air Pollution: a Study in Europe” (ELAPSE) collaboration pools seven cohorts from ...

Changing places to study short-term effects of air pollution on cardiovascular health: a panel study KU Leuven

Hans Scheers, Tim Nawrot, Benoit Nemery de Bellevaux, Lidia Casas Ruiz
BACKGROUND: Short-term exposure to ambient air pollution triggers acute cardiovascular events. Here, we evaluate the association of exposure to ambient air pollution with two intermediate cardiovascular endpoints: blood pressure and carotid stiffness. METHODS: In a one-year panel study, we included 20 healthy volunteers (10 male-female couples aged 59-75 years) with air pollution and health parameters measured every two months at their region of ...

Air pollution and ST-elevation myocardial infarction: A case-crossover study of the Belgian STEMI registry 2009-2013 Universiteit Antwerpen KU Leuven Vrije Universiteit Brussel

J. F. Argacha, P. Collart, A. Wauters, P. Kayaert, S. Lochy, D. Schoors, J. Sonck, T. de Vos, M. Forton, O. Brasseur, et al.
Background: Previous studies have shown that air pollution particulate matter (PM) is associated with an increased risk for myocardial infarction. The effects of air pollution on the risk of ST-elevation myocardial infarction (STEMI), in particular the role of gaseous air pollutants such as NO2 and O-3 and the susceptibility of specific populations, are still under debate. Methods: All patients entered in the Belgian prospective STEMI registry ...

Air pollution impacts on forests in a changing climate Universiteit Gent

Martin Lorenz, Nicholas Clarke, Elena Paoletti, Andrzej Bytnerowicz, Nancy Grulke, Natalia Lukina, Hiroyuki Sase, Jeroen Staelens
Growing awareness of air pollution effects on forests has, from the early 1980s on, led to intensive forest damage research and monitoring. This has fostered air pollution control, especially in Europe and North America, and to a smaller extent also in other parts of the world. At several forest sites in these regions, there are first indications of a recovery of forest soil and tree conditions that may be attributed to improved air quality. ...