Publicaties
Trypanosoma vivax GM6 antigen: a candidate antigen for diagnosis of African animal trypanosomosis in cattle Instituut voor Tropische Geneeskunde
M. tuberculosis T cell epitope analysis reveals paucity of antigenic variation and identifies rare variable TB antigens Instituut voor Tropische Geneeskunde
Pathogens that evade adaptive immunity typically exhibit antigenic variation. By contrast, it appears that although the chronic human tuberculosis (TB)-causing pathogen Mycobacterium tuberculosis needs to counter host T cell responses, its T cell epitopes are hyperconserved. Here we present an extensive analysis of the T cell epitopes of M. tuberculosis. We combined population genomics with experimental immunology to determine the number and ...
Furan oxidation cross-link methodology: towards new approaches in antigene and antisense strategy Universiteit Gent
Furan oxidation cross-link methodology: towards new approaches in antigene and antisense strategy Universiteit Gent
Schistosoma mansoni: characterization of two circulating polysaccharide antigens and the immunological response to these antigens in mouse, hamster, and human infections Instituut voor Tropische Geneeskunde
Serodiagnosis of imported schistosomiasis by a combination of a commercial indirect hemagglutination test with Schistosoma mansoni adult worm antigens and an enzyme-linked immunosorbent assay with S. mansoni egg antigens Instituut voor Tropische Geneeskunde
A simple quantitative affinity capturing assay of poliovirus antigens and subviral particles by single-domain antibodies using magnetic beads. Vrije Universiteit Brussel
Diagnóstico Serológico de Tuberculosis; Utilización del antÃgeno P32 y el antÃgeno SLIV, para el diagnóstico rápido y precoz de la tuberculosis por la serologÃa (ELISA) en el Hospital Regional IHSS en San Pedro Sula, Honduras Instituut voor Tropische Geneeskunde
Systematic review on antigens for serodiagnosis of visceral leishmaniasis, with a focus on East Africa Instituut voor Tropische Geneeskunde
Background
Accurate and accessible diagnosis is key for the control of visceral leishmaniasis (VL). Yet, current diagnostic tests for VL have severe limitations: they are invasive or not suitable as point of care (POC) test or their performance is suboptimal in East Africa. We analysed the antigens in the VL serodiagnostics development pipeline to identify shortcomings and to propose strategies in the development of an alternative POC ...