Publicaties
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Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology KU Leuven
In this consensus document we summarize the current knowledge on major asthma, rhinitis, and atopic dermatitis endotypes under the auspices of the PRACTALL collaboration platform. PRACTALL is an initiative of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology aiming to harmonize the European and American approaches to best allergy practice and science. Precision medicine is of ...
Stepwise approach towards adoption of allergen immunotherayp for allergic rhinitis and asthma patients in daily pracice in Belgium: a BelSACI-Abeforcal-EUFOREA statement. Vrije Universiteit Brussel KU Leuven Universiteit Antwerpen Universiteit Gent
Allergic rhinitis (AR) effects 23-30 % of the European population with equal prevalence in Belgium. Despite guidelines on the correct use of effective treatment, up to 40 % of AR patients remain uncontrolled. Allergen immunotherapy (AIT) has been shown to improve the level of control up to 84 % of patients being controlled by AIT. Recently, new guidelines for AIT have been publised, supporting the clinical evidence for effectiveness of various ...
A randomized, 5-arm dose finding study with a mite allergoid SCIT in allergic rhinoconjunctivitis patients Universiteit Gent
International consensus statement on allergy and rhinology : allergic rhinitis Universiteit Gent
Background: Critical examination of the quality and validity of available allergic rhinitis (AR) literature is necessary to improve understanding and to appropriately translate this knowledge to clinical care of the AR patient. To evaluate the existing AR literature, international multidisciplinary experts with an interest in AR have produced the International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR). Methods: ...
Real-world benefits of allergen immunotherapy for birch pollen-associated allergic rhinitis and asthma Universiteit Gent
Allergic contact dermatitis caused by sodium metabisulfite : a challenging allergen. A case series and literature review; KU Leuven
BACKGROUND: Sulfites, preservatives and antioxidants used in the cosmetic, pharmaceutical and food industry are contact allergens whose relevance seems to be difficult to establish. OBJECTIVES: To perform a retrospective study on patients patch tested with a sulfite. Materials and methods. Between 1990 and 2010, 2763 patients were patch tested with sodium metabisulfite. The reactions were considered to be relevant if there was a clear ...
Allergic contact dermatitis caused by isopropyl alcohol: a missed allergen? KU Leuven
BACKGROUND: Isopropyl alcohol is a secondary alcohol, a structural isomer of propanol, that is widely used as an industrial solvent and as a preservative and antiseptic in the clinical environment. It is known to be a mild irritant for the eyes and mucous membranes, but is considered to be a weak and infrequent sensitizer. OBJECTIVES: To show that isopropyl alcohol should be considered as a potential allergen in patients with eczema who have ...
The influence of European legislation on the use of diagnostic test allergens for nasal allergen provocation in routine care of patients with allergic rhinitis KU Leuven
In patients with allergic rhinitis (AR), the nasal provocation test (NPT) is the standard procedure to evaluate the clinical response of the nasal mucosa to allergens with a high specificity and sensitivity. In AR, it is the only test that really measures the response of the diseased mucosa to allergens while skin prick test and serum IgE confirm the clinical suspicion of sensitization. Moreover, it is of special relevance in the detection of ...
EAACI Guidelines on Allergen Immunotherapy: Allergic Rhinoconjunctivitis KU Leuven
Allergic rhinoconjunctivitis (AR) is an allergic disorder of the nose and eyes affecting about a fifth of the general population. Symptoms of AR can be controlled with allergen avoidance measures and pharmacotherapy. However, many patients continue to have ongoing symptoms and an impaired quality of life; pharmacotherapy may also induce some side-effects. Allergen immunotherapy (AIT) represents the only currently available treatment that targets ...