Publicaties
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Building a better mobile app marketplace : a legal and governance toolkit for app mediated genomics research Universiteit Gent
Development and field evaluation of the INTER-ACT app, a pregnancy and interpregnancy coaching app to reduce maternal overweight and obesity Universiteit Antwerpen KU Leuven
Background: The interpregnancy and pregnancy periods are important windows of opportunity to prevent excessive gestational weight retention. Despite an overwhelming number of existing health apps, validated apps to support a healthy lifestyle between and during pregnancies are lacking. Objective: To describe the development and evaluation of the INTER-ACT app, which is part of an interpregnancy and pregnancy lifestyle coaching module, to prevent ...
Poems from Ideas of Order: "Lions in Sweden", "Botanist on Alp (No. 1)", and "Botanist on Alp (No. 2)" Universiteit Antwerpen
Using a gamified monitoring app to change adolescents' snack intake: the development of the REWARD app and evaluation design KU Leuven Universiteit Gent
BACKGROUND: As the snacking pattern of European adolescents is of great concern, effective interventions are necessary. Till now health promotion efforts in children and adolescents have had only limited success in changing adolescents' eating patterns and anthropometrics. Therefore, the present study proposes an innovative approach to influence dietary behaviors in youth based on new insights on effective behavior change strategies and ...
Peptides based on the presenilin-APP binding domain inhibit APP processing and Aβ production through interfering with the APP transmembrane domain KU Leuven
Presenilins (PSENs) form the catalytic component of the γ-secretase complex, responsible for intramembrane proteolysis of amyloid precursor protein (APP) and Notch, among many other membrane proteins. Previously, we identified a PSEN1-binding domain in APP, encompassing half of the transmembrane domain following the amyloid β (Aβ) sequence. Based on this, we designed peptides mimicking this interaction domain with the aim to selectively block ...
The Swedish APP mutation alters the effect of genetically reduced BACE1 expression on the APP processing KU Leuven
Inhibition of β-secretase (BACE1) is a key therapeutic approach in Alzheimer's disease (AD), as BACE1 initiates amyloid-β (Aβ) cleavage from the β-amyloid precursor protein (APP). As Aβ reductions in mice lacking one BACE1 allele diverged considerably between studies we investigated the effect of BACE1 knock-out in more detail. With both BACE1 alleles the Swedish mutation (APP23 mice) increased APP processing and shifted it towards the ...
Ahu Motu Toremo Hiva (Poike Peninsula, Easter Island): dynamic architecture of a series of Ahu Universiteit Gent
Ahu Motu Toremo Hiva (Poike Peninsula, Easter Island): Dynamic Architecture of a Series of Ahu KU Leuven
The work undertaken at Ahu Motu Toremo Hiva (Poike Peninsula, Easter Island) between 2004 and 2006 hasbrought to light several unexpected elements: the sequential emplacement of ritual platforms, testifying the use of the sitethat has at least two times been completely rearranged since its initial occupation in the late 13th-14th century AD, thesystematic disassembling of pebble pavements before each phase of abandonment, and the recycling of ...
On Shifting a Nation’s Collective Memory: The Role of Ahn Jung-geun in South Korea’s Foreign Policy Vrije Universiteit Brussel
This article revisits the role that Ahn Jung-geun plays in Korean collective memory today and contrasts this with the Moon administration’s foreign policy. An analysis of Korean collective memory shows that Ahn’s assassination of Ito Hirobumi is heavily emphasized but Ahn’s ultimate goal of bringing peace to Northeast Asia is overlooked. This emphasis is understood through Jan Assmann’s model of collective memory. Based on Aleida Assmann and ...