De ziekte van Alzheimer en AAV9: gebruik van een virusgebaseerd toedieningssysteem voor vector-immunoprofylaxie bij dementie. KU Leuven
Alzheimer’s disease (AD) is the most common form of dementia in the Western World, representing an economic and social cost of billions of euros a year. Given the changing demographics of society, these costs will only increase over the coming decades.
Amyloid plaques, composed of amyloid beta peptide (Abeta), are a defining characteristic of AD. Evidence now suggests that Abeta is central to disease pathogenesis due to its ...