Publicaties

Former studies have demonstrated a strong interest toward the crystallization of CaCO3 polymorphs in solution. Nowadays, CaCO3 crystallization on solid surfaces is extensively being studied using biomolecules as substrates for the control of the growth aiming at various applications of CaCO3. Calcium carbonate exists in an amorphous state, as three anhydrous polymorphs (aragonite, calcite and vaterite), and as two hydrated polymorphs ...

Cell-based immunotherapies hold great promise for the future treatment of cancer. The success of these therapies demonstrated the power of harnessing the immune system to eradicate tumors. It is also becoming clear that the type of cancer cell death determines the antitumor immune response and, therefore, contributes to the efficiency of anti-cancer therapy and long-term survival of patients1. Since tumors often develop resistance to apoptosis ...

Immunotherapies hold great promise for the future treatment of cancer. It is also becoming clear that type of cancer cell death determines the antitumor immune response and, therefore, contributes to the efficiency of anti-cancer therapy and long-term survival of patients. Since tumors often develop resistance to apoptosis and necroptosis, triggering these processes is not always the optimal strategy. That is why it is crucial to select the ...

Polymeric hydrogels are an important class of functional soft materials composed of a large variety of neutral or charged hydrophilic macromolecules cross-linked chemically or physically in an aqueous environment. The water-rich nature of hydrogels resembles biological tissues opening up opportunities for their application in biomedical areas, such as tissue engineering. However, the mere presence of a matrix for cell growth is often not ...

Crystalline covalent triazine frameworks (CTFs) with intrinsic porosity and high stability are an excellent platform for engineering luminescence properties, as their building blocks and guest ions are all important factors in light emission. Herein, a highly crystalline bipyridine-based CTF (Bipy-CTF) is synthesized under mild conditions. The controlled tethering of lanthanide ions (Ln = Eu3+ and Tb3+) onto Bipy-CTF combined with selective ...

The ion exchange processes and phase formation were studied by varying the properties of 1D barium titanate nanostructures. Temperature-, timeand alkalinity-dependent experiments were performed to study the BaTiO3 formation mechanism involving the generation of chemical sites which induced in situ transformation and dissolution-precipitation reactions occurring in a hydrothermal treatment procedure. As a result of the hydro thermal synthesis, ...

To develop materials for drug delivery and tissue engineering and to study their efficiency with respect to ossification, it is necessary to apply physicochemical and biological analyses. The major challenge is labor-intensive data mining during synthesis and the reproducibility of the obtained data. In this work, we investigated the influence of time and temperature on the reaction yield, the reaction rate, and the size, shape, and phase of the ...

Carbone nanotubes (CNTs) possess distinct properties, for example, hardness, which is very complementary to biologically relevant soft polymeric and protein materials. Combining CNTs with bio-interfaces leads to obtaining new materials with advanced properties. In this work, we have designed novel organic-inorganic hybrid coatings by combining CNTs with gellan gum (GG) hydrogels. The surface topography of the samples is investigated using ...

In recent years, luminescent materials doped with Ln(3+) ions have attracted much attention for their application as optical thermometers based on both downshifting and upconversion processes. This study presents research done on the development of highly sensitive optical thermometers in the physiological temperature range based on poly(methyl methacrylate) (PMMA) films doped with two series of visible Ln(3+) complexes (Ln(3+)=Tb3+, Eu3+, and ...

As the next generation of materials for bone reconstruction, we propose a multifunctional bioactive platform based on biodegradable piezoelectric polyhydroxybutyrate (PHB) fibrous scaffolds for tissue engineering with drug delivery capabilities. To use the entire surface area for local drug delivery, the scaffold surface was uniformly biomineralized with biocompatible calcium carbonate (CaCO3) microparticles in a vateriteU+2013calcite polymorph ...