Publicaties
Auranofin repurposing for lung and pancreatic cancer Universiteit Antwerpen
Background This study explores the repurposing of Auranofin (AF), an anti-rheumatic drug, for treating non-small cell lung cancer (NSCLC) adenocarcinoma and pancreatic ductal adenocarcinoma (PDAC). Drug repurposing in oncology offers a cost-effective and time-efficient approach to developing new cancer therapies. Our research focuses on evaluating AF's selective cytotoxicity against cancer cells, identifying RNAseq-based biomarkers to predict AF ...
A novel line-scan algorithm for unsynchronised dynamic measurements Universiteit Antwerpen
In non-destructive inspections today, the size of the sample being examined is often limited to fit within the field of view of the camera being used. When examining larger specimens, multiple image sequences need to be stitched together into one image. Due to uneven illumination, the combined image may have artificial defects. This manuscript provides a solution for performing line-scan measurements from a sample and combining the images to ...
Performance assessment of discrete wavelet transform for de-noising of FBG sensors signals embedded in asphalt pavement Universiteit Antwerpen
In recent years, the Fiber Bragg Grating (FBG) sensor technology has been increasingly utilized as an optical measurement system in various engineering applications, particularly for structural health monitoring (SHM) purposes. This trend can be attributed to the inherent benefits of FBG sensors, such as their small size, immunity to electromagnetic interference, resistance to corrosion, and high accuracy and sensitivity. Various factors cause ...
Into a rapid polymer characterization employing optical measurement systems and high-power ultrasonic excitation Universiteit Antwerpen
This study presents a novel methodology for estimating the master curve of the complex modulus of viscoelastic materials using a combination of optical measurement systems and ultrasonic excitation. Traditional techniques for characterizing properties of viscoelastic materials are often time-consuming and encounter limitations that hinder their accuracy at high strain rates. To address this, a method was proposed that leverages two optical ...
Seaweed growth monitoring with a low-cost vision-based system Universiteit Antwerpen
In this paper, we introduce a method for automated seaweed growth monitoring by combining a low-cost RGB and stereo vision camera. While current vision-based seaweed growth monitoring techniques focus on laboratory measurements or above-ground seaweed, we investigate the feasibility of the underwater imaging of a vertical seaweed farm. We use deep learning-based image segmentation (DeeplabV3+) to determine the size of the seaweed in pixels from ...
On the angular control of rotating lasers by means of line calculus on hyperboloids Universiteit Antwerpen
We propose a new paradigm for modelling and calibrating laser scanners with rotation symmetry, as is the case for lidars or for galvanometric laser systems with one or two rotating mirrors. Instead of bothering about the intrinsic parameters of a physical model, we use the geometric properties of the device to model it as a specific configuration of lines, which can be recovered by a line-data-driven procedure. Compared to universal data-driven ...
A phase correlation based peak detection method for accurate shape from focus measurements Universiteit Antwerpen
Estimating a 3D shape from 2D images is a classic computer vision problem. Shape from focus is a commonly used method for this purpose. With shape from focus, 3D depth is estimated using a so-called focus measure operator. Pixel focus follows a Gaussian-like distribution in which the location of the peak is an indicator of the 3D depth. Locating the peak in this distribution is complicated due to noise coming from various sources. We investigate ...
Design and metrological analysis of a backlit vision system for surface roughness measurements of turned parts Universiteit Antwerpen
The focus of this study is to design a backlit vision instrument capable of measuring surface roughness and to discuss its metrological performance compared to traditional measurement instruments. The instrument is a non-contact high-magnification imaging system characterized by short inspection time which opens the perspective of in-line implementation. We combined the use of the modulation transfer function to evaluate the imaging conditions ...
Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer Universiteit Antwerpen
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal diseases, characterized by a treatment-resistant and invasive nature. In line with these inherent aggressive characteristics, only a subset of patients shows a clinical response to the standard of care therapies, thereby highlighting the need for a more personalized treatment approach. In this study, we comprehensively unraveled the intra-patient response heterogeneity and ...