Beta-lactam hypersensitivity Universiteit Antwerpen
A new cannabis allergen in Northwestern Europe Universiteit Antwerpen
A minority of Northwestern European cannabis allergic patients display IgE reactivity to oxygen-evolving enhancer protein 2 by specific IgE and basophil activation tests. All these patients are co-sensitized to Can s 3, the nonspecific lipid transfer protein and major allergen of Cannabis sativa.
Cross-reactivity in IgE-mediated allergy to cefuroxime Universiteit Antwerpen
Medical algorithms Universiteit Antwerpen
A systematic approach to both diagnosis and investigations is essential, when investigating a patient with a suspected perioperative hypersensitivity reaction. The perioperative setting is extremely complex with documented and undocumented exposures to many different drugs and substances. In addition, the effect of anaesthetic drugs and surgical procedure may mimic hypersensitivity. To ensure that all these complexities are addressed, ...
Clinical features and survival of patients with indolent systemic mastocytosis defined by the updated WHO classification Universiteit Antwerpen
Background: In indolent systemic mastocytosis (ISM), several risk factors of disease progression have been identified. Previous studies, performed with limited patient numbers, have also shown that the clinical course in ISM is stable and comparable to that of cutaneous mastocytosis (CM). The aim of this project was to compare the prognosis of patients with ISM with that of patients with CM. Methods: We employed a dataset of 1993 patients from ...
Flow cytometric basophil activation tests Universiteit Antwerpen
Background Staining of exteriorized basophil granule matrix by fluorescent avidin might be a reliable technique to monitor basophil degranulation. This study compares the avidin‐based technique with the upregulation of CD203c and appearance of CD63 in response to various stimuli. Methods Fourteen individuals responsive to anti‐IgE, nine healthy controls, and five birch pollen‐allergic patients, and five nonresponders were studied. Activation ...