Publicaties
Current state and guidance on arterial spin labeling perfusion MRI in clinical neuroimaging Universiteit Gent
This article focuses on clinical applications of arterial spin labeling (ASL) and is part of a wider effort from the International Society for Magnetic Resonance in Medicine (ISMRM) Perfusion Study Group to update and expand on the recommendations provided in the 2015 ASL consensus paper. Although the 2015 consensus paper provided general guidelines for clinical applications of ASL MRI, there was a lack of guidance on disease-specific ...
Investigation of technical variability in ASL data using MR phantoms Universiteit Gent
Introduction: Arterial Spin Labeling (ASL) is a non-invasive MR imaging technique used to quantify perfusion, showing high promise for the diagnosis of many neurological and psychiatric disorders1. However, the clinical application of ASL is limited due to the possible influence of technical factors such as scanner and coil variability. To address this limitation, MR phantoms, such as the Quantitative Arterial Spin Labeling Perfusion Reference ...
Imaging blood-brain barrier dysfunction : a state-of-the-art review from a clinical perspective Universiteit Gent Vrije Universiteit Brussel
The blood-brain barrier (BBB) consists of specialized cells that tightly regulate the in- and outflow of molecules from the blood to brain parenchyma, protecting the brain's microenvironment. If one of the BBB components starts to fail, its dysfunction can lead to a cascade of neuroinflammatory events leading to neuronal dysfunction and degeneration. Preliminary imaging findings suggest that BBB dysfunction could serve as an early diagnostic and ...
Advanced MR techniques for preoperative glioma characterization : part 1 Universiteit Gent
Preoperative clinical magnetic resonance imaging (MRI) protocols for gliomas, brain tumors with dismal outcomes due to their infiltrative properties, still rely on conventional structural MRI, which does not deliver information on tumor genotype and is limited in the delineation of diffuse gliomas. The GliMR COST action wants to raise awareness about the state of the art of advanced MRI techniques in gliomas and their possible clinical ...
Micro- to macroscale magnetic resonance imaging of glioma Universiteit Gent
Arterial spin labeling perfusion MRI : tackling technical and physiological variability Universiteit Gent
Application of frozen Thiel-embalmed specimens for radiotherapy delineation guideline development : a method to create accurate MRI-enhanced CT datasets Universiteit Gent
Purpose Thiel embalming followed by freezing in the desired position and acquiring CT + MRI scans is expected to be the ideal approach to obtain accurate, enhanced CT data for delineation guideline development. The effect of Thiel embalming and freezing on MRI image quality is not known. This study evaluates the above-described process to obtain enhanced CT datasets, focusing on the integration of MRI data obtained from frozen, Thiel-embalmed ...