Publicaties

Age-related macular degeneration (AMD) is an age-related disorder that is a global public health problem. The non-enzymatic Maillard reaction results in the formation of advanced glycation end products (AGEs). Accumulation of AGEs in drusen plays a key role in AMD. AGE-reducing drugs may contribute to the prevention and treatment of AGE-related disease. Fructosamine oxidase (FAOD) acts on fructosyl lysine and fructosyl valine. Based upon the ...

Passive dosimeters enabling accurate measurement of doses from gamma rays to visible light are necessary to ensure efficient utilization of electromagnetic radiation in numerous fields like medical diagnostics and industrial manufacturing. The specific requirements for dosimeters in terms of dosimetry range, sensitivity, accuracy, and stability for each application have led to the development of various dosimeters based on new materials and new ...

Covalent organic frameworks (COFs) have gained a lot of attention in recent years due to their tunable porosity and functionality. Porphyrin-containing COFs have proven effective in several applications such as photo- and electrocatalysis. However, a standard reproducible procedure for the synthesis of crystalline metalated porphyrin COFs remains challenging. In this work, a general procedure using an "assembler" approach based on preorientation ...

Unexpected behavior is observed when charge pumping is performed on silicon carbide MOSFETs with a thermally grown silicon dioxide gate dielectric. Supported by experimental evidence, two root causes are proposed: the trap density and the channel non-equilibrium. These are difficult to overcome experimentally due to limitations by oxide breakdown and doping variation along the channel, respectively. A correct interpretation then requires a 2D ...

Attenuated total reflection (ATR) microscope Fourier transform infrared (micro-FTIR) spectroscopy was used to investigate the dinosporin composition in the walls of modern, organic-walled dinoflagellate resting cysts (dinocysts). Variable cyst wall compositions were observed, which led to the erection of four spectrochemical groups, some with striking similarities to other resistant biomacromolecules such as sporopollenin and algaenan. ...

Acritarchs are an informal, polyphyletic, and morphologically heterogenous group of organic- walled microfossils of unknown biological affinity. Some acritarchs share morphological similarities with certain microplankton resting stages (from e.g., dinoflagellates, prasinophycean-, chlorophycean-, and zygnematophycean green algae), others with miospores, egg cases of zooplankton, or even skeletal fragments of higher organisms. For most extant ...

Dinoflagellates are an extant group of unicellular, eukaryotic microalgae occurring in a wide range of aquatic environments. They can form resistant, organic-walled resting stages (dinocysts); the earliest body fossils appear in the Middle Triassic. Dinocyst walls are composed of a heavily cross-linked, nitrogenous, cellulose-like carbohydrate, ‘dinosporin’, which is compositionally distinct from other resistant biomacromolecules such as ...