Sterile triggers drive joint inflammation in TNF‐ and IL-1β‐dependent mouse arthritis models Universiteit Gent Vlaams Instituut voor Biotechnologie
Arthritis is the most common extra-intestinal complication in inflammatory bowel disease (IBD). Conversely, arthritis patients are at risk for developing IBD and often display subclinical gut inflammation. These observations suggest a shared disease etiology, commonly termed "the gut-joint-axis." The clinical association between gut and joint inflammation is further supported by the success of common therapeutic strategies and microbiota ...