Titel Deelnemers "Korte inhoud" "A review of sustainability indicators for biobased chemicals" "Sophie VAN SCHOUBROECK, Miet VAN DAEL, Steven VAN PASSEL, Robert MALINA" "Companies dealing with chemical products have to cope with large amounts of waste and environmental risk due to the use and production of toxic substances. Against this background, increasing attention is being paid to “green chemistry” and the translation of this concept into biobased chemicals. Given the multitude of economic, environmental and societal impacts that the production and use of biobased chemicals have on sustainability, assessment approaches need to be developed that allow for measurement and comparison of these impacts. To evaluate sustainability in the context of policy and decision-making, indicators are generally accepted means. However, sustainability indicators currently predominantly exist for low-value applications in the bioeconomy, like bioenergy and biofuels. In this paper, a review of the state-of-the-art sustainability indicators for biobased chemicals is conducted and a gap analysis is performed to identify indicator development needs. Based on the analysis, a clear hierarchy within the concept of sustainability is found where the environmental aspect dominates over economic and social indicators. All one-dimensional indicator-sets account for environmental impacts (50%), whereas two-dimensional sets complement the environmental issues with economic indicators (34%). Moreover, even the sets encompassing all three sustainability dimensions (16%) do not account for the dynamics and interlinkages between the environment, economy and society. Using results from the literature review, an indicator list is presented that captures all indicators currently used within sustainability assessment of biobased chemicals. Finally, a framework is proposed for future indicator selection using a stakeholder survey to obtain a prioritized list of sustainability indicators for biobased chemicals." "Biobased chemicals : 1,2,4-benzenetriol, selective deuteration and dimerization to bifunctional aromatic compounds" "Caelan Randolph, Ciaran W. Lahive, Selim Sami, Remco Havenith, Hero J. Heeres, Peter J. Deuss" "Life cycle optimization of the supply chain for biobased chemicals with local biomass resources" "Carlos García-Velásquez, Christof Defryn, Yvonne van der Meer" "Developing a biobased chemical industry that copes with the current environmental challenges relies on understanding the influence of the different stages of the value chain on economic and environmental performance. This paper investigates the use of a life cycle optimization framework to assess trade-offs between environmental and economic criteria for designing supply chains for biobased polyethylene terephthalate as a case study. A multi-objective optimization model was formulated to account for the environmental impacts (through life cycle assessment) and total costs (through life cycle costing) of the case study. High environmental priority (w = 0.9) in the design of the supply chain resulted in environmental gains (in 8 out of 9 midpoint indicators) with low increments (" "Muconic acid isomers as platform chemicals and monomers in the biobased economy" "Ibrahim Khalil, Greg QUINTENS, Tanja JUNKERS, Michiel Dusselier" "Muconic acid (MA) is a high value-added dicarboxylic acid with conjugated double bonds, presenting three isomeric forms, i.e., cis,cis-MA, cis,trans-MA and trans,trans-MA. Its production is garnering increased interest owing to its potential as a starting material for the synthesis of value-added products as well as by being a versatile monomer for the production of specialty polymers. This review presents a systematic overview of production and synthesis routes to MA isomers as well as the routes for its final valorization. The production of MA through chemical pathways and the progress developed in the biotechnological pathways will be discussed. Traditional and new processes for achieving successful isomerization into the value-added trans,trans form of MA are also discussed and compared, with their constraints and possible solutions. The valorization of the three different isomers of MA into value-added chemicals such as adipic or terephthalic acids and MA polymers are summarized. Finally, the review concludes with a thorough summary, a practical insights section and an outlook. This work thus offers new perspectives and guidelines to tackle the challenges in MA chemistry, especially when aiming to combine an efficient biotechnological production of MA with its valorization." "Branching-First: Synthesizing C-C Skeletal Branched Biobased Chemicals from Sugars" "Aron Deneyer, Michiel Dusselier, Bert Sels" "© 2018 American Chemical Society. A novel strategy to biobased chemicals with a branched carbon skeleton is introduced. Hereto, small sugars, such as 1,3-dihydroxyacetone, are coupled catalytically to obtain branched C6 sugars, such as dendroketose, in high yield at mild conditions. By bringing this branching step up front, at the level of the sugar feedstock (branching-first), new opportunities for the synthesis of useful chemicals arise. Here, we show that the branched sugar can be efficiently valorized into (i) new branched polyols and (ii) short branched alkanes. The first route preserves most of the original sugar functionality by hydrogenation with Ru/C and renders access to branched polyols with three primary alcohol groups. These molecules are potentially interesting as plasticizers, cross-linkers, or detergent precursors. The second valorization route demonstrates a facile hydrodeoxygenation of the branched sugars toward their corresponding branched alkanes (e.g., 2-methylpentane). The highest alkanes yields (>65 mol % C) are obtained with a Rh/C redox metal catalyst in a biphasic catalytic system, following a HDO mechanism. In the short term, commercial integration of these monobranched alkanes, in contrast to branched polyols, is expected to be straightforward because of their drop-in character and well-known valuable octane booster role when present in gasoline. Accordingly, the branching-first concept is also demonstrated with other small sugars (e.g., tetroses) enabling the production of branched C6-C8 sugars and thus also branched C5-C8 alkanes after HDO." "A techno-sustainability assessment framework: indicator selection and integrated method for sustainability analysis of biobased chemicals" "Sophie VAN SCHOUBROECK" "Sustainability indicators for biobased chemicals: A Delphi study using Multi- Criteria Decision Analysis" "Sophie VAN SCHOUBROECK, Johan SPRINGAEL, Miet VAN DAEL, Robert MALINA, Steven VAN PASSEL" "Biobased chemistry has gained interest and has the potential to tackle some of the sustainability challenges the chemical industry must endure. Sustainability impacts need to be evaluated and monitored to highlight the advantages and pitfalls of different biobased routes over the entire product life cycle. This study aims for expert consensus concerning indicators needed and preferred for sustainability analysis of biobased chemicals in Europe. Experts are consulted by means of a Delphi method with stakeholders selected from three core groups: the private, public and academic sector. Best-Worst Scaling (BWS) is performed to gather data on the prioritization of the sustainability indicators per respondent. Afterwards, Multi-Criteria Decision Analysis (MCDA) is used to develop a consensus ranking among the experts. The results show that GHG emissions, market potential and acceptance of biobased materials are deemed the most crucial indicators for respectively environmental, economic and social sustainability. Expert consensus is positive in all three sustainability domains, with the strongest consensus measured for environmental sustainability showing a median Kendall’s τ of 0.63 (τ ranging from -1 to 1) and the weakest consensus found within social sustainability showing a median Kendall’s τ of 0.50. Further research can apply the ranked indicators on specific case studies to evaluate the practicability of the defined indicator set." "In situ product recovery of bio-based industrial platform chemicals : a guideline to solvent selection" "Pieter De Brabander, Evelien Uitterhaegen, Ellen Verhoeven, Cedric Vander Cruyssen, Karel De Winter" "Lactic acid as a platform chemical in the biobased economy: the role of chemocatalysis" "Michiel Dusselier, Pieter Van Wouwe, Annelies Dewaele, Ekaterina Makshina, Bert Sels" "Upcoming bio-refineries will be at the heart of the manufacture of future transportation fuels, chemicals and materials. A narrow number of platform molecules are envisioned to bridge nature's abundant polysaccharide feedstock to the production of added-value chemicals and intermediate building blocks. Such platform molecules are well-chosen to lie at the base of a large product assortment, while their formation should be straightforward from the refined biomass, practical and energy efficient, without unnecessary loss of carbon atoms. Lactic acid has been identified as one such high potential platform. Despite its established fermentation route, sustainability issues-like gypsum waste and cost factors due to multi-step purification and separation requirements-will arise as soon as the necessary orders of magnitude larger volumes are needed. Innovative production routes to lactic acid and its esters are therefore under development, converting sugars and glycerol in the presence of chemocatalysts. Moreover, catalysis is one of the fundamental routes to convert lactic acid into a range of useful chemicals in a platform approach. This contribution attempts a critical overview of all advances in the field of homogeneous and heterogeneous catalysis and recognises a great potential of some of these chemocatalytic approaches to produce and transform lactic acid as well as some other promising α-hydroxy acids. © 2013 The Royal Society of Chemistry." "Lactic acid as a platform chemical in the biobased economy: the role of chemocatalysis" "Michiel Dusselier, Pieter Van Wouwe, Annelies Dewaele, Ekaterina Makshina, Bert Sels"