Titel Deelnemers "Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor" "Zuzanna Drebert, Mark MacAskill, Dahlia Doughty-Shenton, Karolien De Bosscher, Marc Bracke, Patrick WF Hadokwe, Ilse Beck" "When Neighbors Talk: Colon Cancer Cell Invasion and Tumor Microenvironment Myofibroblasts" "Jolien Bridelance, Zuzanna Drebert, Olivier De Wever, Marc Bracke, Ilse Beck" "A gamut of undiscovered electrophysiological effects produced by Tityus serrulatus toxin 1 on NaV-type isoforms" "Steve Peigneur, Camilla T Cologna, Caroline M Cremonez, Bea G Mille, Manuela B Pucca, Eva Cuypers, Eliane C Arantes, Jan Tytgat" "Curious discoveries in antiviral drug development: The role of serendipity" "Erik De Clercq" "Simple HPLC-UV method for the quantification of metformin in human plasma with one step protein precipitation" "Himal Paudel Chhetri, Panna Thapa, Ann Van Schepdael" "Authors’ reply: Using the air pouch model for assessing in vivo inflammatory activity of nanoparticles" "Jennifer Vandooren, Ghislain Opdenakker" "Author's reply: To PMID 24379662." "Jennifer Vandooren, Ghislain Opdenakker" "Prebiotics to fight diseases: reality or fiction?" "Francesca Di Bartolomeo, Justyna Startek, Wim Van den Ende" "Bacteria living in the gastrointestinal tract are crucial for human health and disease occurrence. Increasing the beneficial intestinal microflora by consumption of prebiotics, which are 'functional foods', could be an elegant way to limit the number and incidence of disorders and to recover from dysbiosis or antibiotic treatments. This review focuses on the short-chain low-digestible carbohydrates (LDCs) which are metabolized by gut microbiota serving as energy source, immune system enhancers or facilitators of mineral uptake. Intake of foods containing LDCs can improve the state of health and may prevent diseases as for example certain forms of cancer. Given the large number of different molecules belonging to LDCs, we focused our attention on fructans (inulin, fructo-oligosaccharides), galacto-oligosaccharides and resistant starches and their therapeutic and protective applications. Evidence is accumulating that LDCs can inhibit bacterial and viral infections by modulating host defense responses and by changing the interactions between pathogenic and beneficial bacteria. Animal studies and studies on small groups of human subjects suggest that LDCs might help to counteract colorectal cancer, diabetes and metabolic syndrome. The action mechanisms of LDCs in the human body might be broader than originally thought, perhaps also including reactive oxygen species scavenging and signaling events." "Optimizing pharmacotherapy in older patients : a European perspective" "Denis O'Mahony, Antonio Cherubini, Mirko Petrovic" "SUBCHRONIC ADMINISTRATION OF TETRABENAZINE AS A PUTATIVE MOUSE MODEL FOR DEPRESSION" "Zsuzsanna Callaerts-Végh, Sam Willems, Rudi D'Hooge"