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Synthesis of fluorescent ristocetin aglycon derivatives with remarkable antibacterial and antiviral activities

Tijdschriftbijdrage - Tijdschriftartikel

Isoindole and benzoisoindole derivatives of ristocetin aglycon have been prepared by reaction with o-phthalaldehyde or naphthalene-2,3-dialdehyde and various thiols. The new compounds exhibited potent antibacterial and anti-influenza virus activity. The cluster forming and fluorescent properties of the aglycon derivatives were also studied.
Tijdschrift: European Journal of Medicinal Chemistry
ISSN: 0223-5234
Volume: 58
Pagina's: 361 - 367
Jaar van publicatie:2012
Trefwoorden:Organische en medische scheikunde