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The operationalization of fatigue in frailty scales: a systematic review

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Purpose: To identify the different fatigue items in existing frailty scales. Methods: PubMed, Web of Knowledge and PsycINFO were systematically screened for frailty scales. 133 articles were included, describing 158 frailty scales. Fatigue items were extracted and categorized in 4 fatigue constructs: “mood state related tiredness”, “general feeling of tiredness”, “activity based feeling of tiredness” and “resistance to physical tiredness”. Results: 120 fatigue items were identified, of which 100 belonged to the construct “general feeling of tiredness” and only 9 to the construct “resistance to physical tiredness”. 49,4% of the frailty scales included at least 1 fatigue item, representing 15 ± 9,3% of all items in these scales. Fatigue items have a significantly higher weight in single domain (dominantly physical frailty scales) versus multi domain frailty scales (21 ± 3.2 versus 10.6 ± 9.8%, p=<0,05). Conclusion: Fatigue is prominently represented in frailty scales, covering a great diversity in fatigue constructs and underlying pathophysiological mechanisms by which fatigue relates to frailty. Although fatigue items were more prevalent and had a higher weight in physical frailty scales, the operationalization of fatigue leaned more towards psychological constructs. This review can be used as a reference for choosing a suitable frailty scale depending on the type of fatigue of interest.

Tijdschrift: Ageing Research Reviews
ISSN: 1568-1637
Volume: 53
Jaar van publicatie:2019
Trefwoorden:Frailty assessment, Fatigue, Tiredness, Aged, Frail elderly
  • DOI: https://doi.org/10.1016/j.arr.2019.100911
  • ORCID: /0000-0003-4999-5902/work/68876922
  • ORCID: /0000-0002-5752-6498/work/68877819
  • ORCID: /0000-0002-9692-9513/work/68878263
  • ORCID: /0000-0003-4084-6898/work/68879461
  • ORCID: /0000-0002-8308-4099/work/68879608
  • ORCID: /0000-0001-6229-0742/work/68880860
  • Scopus Id: 85066956116
  • ArticleNumber: 100911