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Lower limb muscle volume estimation from maximum cross-sectional area and muscle length in cerebral palsy and typically developing individuals

Tijdschriftbijdrage - Tijdschriftartikel

Background: Deficits in muscle volume may be a significant contributor to physical disability in young peoplewith cerebral palsy. However, 3D measurements of muscle volume using MRI or 3D ultrasound may be difficultto make routinely in the clinic. We wished to establish whether accurate estimates of muscle volume could bemade from a combination of anatomical cross-sectional area and length measurements in samples of typicallydeveloping young people and young people with bilateral cerebral palsy.Methods: Lower limb MRI scans were obtained from the lower limbs of 21 individuals with cerebral palsy(14.7 ± 3 years, 17 male) and 23 typically developing individuals (16.8 ± 3.3 years, 16 male). The volume,length and anatomical cross-sectional area were estimated from six muscles of the left lower limb.Findings: Analysis of Covariance demonstrated that the relationship between the length*cross-sectional area andvolume was not significantly different depending on the subject group. Linear regression analysis demonstratedthat the product of anatomical cross-sectional area and length bore a strong and significant relationship to themeasured muscle volume (R2 values between 0.955 and 0.988) with low standard error of the estimates of 4.8 to8.9%.Interpretation: This study demonstrates that muscle volume may be estimated accurately in typically developingindividuals and individuals with cerebral palsy by a combination of anatomical cross-sectional area and musclelength. 2D ultrasound may be a convenient method of making these measurements routinely in the clinic.
Tijdschrift: Clinical Biomechanics
ISSN: 0268-0033
Volume: 51
Pagina's: 40 - 44
Jaar van publicatie:2017