Get what you want : identifying antibodies against pre-defined epitopes on Frizzled receptors

In this issue of Structure, Ge et al. report an epitope-directed strategy to select antibodies specific for Frizzled subtypes. Structural and biochemical analyses provide mechanistic insights into the target binding of the isolated antibodies that could guide the design of reagents and therapeutics targeting distinct Frizzled receptors.

Jaar van publicatie:2023

Toegankelijkheid:Open