Field validity and feasibility of four techniques for the detection of Trichuris in simians: a model for monitoring drug efficacy in public health?

Soil-transmitted helminths, such as Trichuris trichiura, are of major concern in public health. Current efforts to control these helminth infections involve periodic mass treatment in endemic areas. Since these large-scale interventions are likely to intensify, monitoring the drug efficacy will become indispensible. However, studies comparing detection techniques based on sensitivity, fecal egg counts (FEC), feasibility for mass diagnosis and drug efficacy estimates are scarce.

Jaar van publicatie:2009

Trefwoorden:Animals,Anthelmintics,Anthelmintics: therapeutic use,Cercopithecus aethiops,Disease Models, Animal,Drug Monitoring,Drug Monitoring: methods,Feasibility Studies,Feces,Feces: parasitology,Macaca,Papio hamadryas,Parasite Egg Count,Parasite Egg Count: methods,Public Health,Sensitivity and Specificity,Trichuriasis,Trichuriasis: diagnosis,Trichuriasis: drug therapy,Trichuriasis: prevention control,Trichuris,Trichuris: isolation purification