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Divergent synthetic approach to 6''-modified U+03B1-GalCer analogues

Tijdschriftbijdrage - Tijdschriftartikel

Ondertitel:Divergent synthetic approach to 6 ''-modified alpha-GalCer analogues
A synthetic approach is presented for the synthesis of galacturonic acid and D-fucosyl modified KRN7000. The approach allows for late-stage functionalisation of both the sugar 6 ''-OH and the sphingosine amino groups, which enables convenient synthesis of promising 6 ''-modified KRN7000 analogues.
Tijdschrift: ORGANIC & BIOMOLECULAR CHEMISTRY
ISSN: 1477-0520
Issue: 24
Volume: 9
Pagina's: 8413 - 8421
Jaar van publicatie:2011